15 Participants Needed

Postural Training for Parkinson's Disease

(SegwayPD Trial)

YC
SS
Overseen BySubaryani Soedirdjo, Ph.D.
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Texas Southwestern Medical Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

Will I have to stop taking my current medications?

The trial does not specify if you need to stop taking your current medications, but it requires that you have been stable on your medication for at least 1 month before participating.

What data supports the effectiveness of the treatment Sensory-Augmented Postural Training for Parkinson's Disease?

Research shows that balance training with augmented visual feedback and multimodal sensory feedback can improve postural control and gait in Parkinson's patients, suggesting that Sensory-Augmented Postural Training may also be effective.12345

Is postural training for Parkinson's disease safe for humans?

Research shows that sensory feedback devices, like virtual sensory feedback and Equistasi, used for postural training in Parkinson's disease are generally safe and well-tolerated, with no reported side effects.13467

How is Sensory-Augmented Postural Training different from other treatments for Parkinson's disease?

Sensory-Augmented Postural Training is unique because it uses enhanced sensory feedback, such as visual or virtual reality elements, to improve balance and postural control in Parkinson's patients, which is different from traditional balance training methods.248910

What is the purpose of this trial?

The purpose of this study is to examine the safety and efficacy of postural training emphasized on the integration of multiple sensory information into motor control in individuals with PD. This project is a proof-of-concept study to assess the effectiveness of postural training using Segway, which serves a platform to provide augmented and continuous proprioceptive and visuospatial information during postural training.

Research Team

YD

Yasin Dhaher, Ph.D.

Principal Investigator

University of Texas Southwestern Medical Center

Eligibility Criteria

This trial is for individuals aged 50-85 with idiopathic Parkinson's Disease at a moderate stage (Hoehn and Yahr stage III), who can stand and walk unaided for 5 minutes, whether on or off medication. They must have been stable on their current medication for at least one month.

Inclusion Criteria

I can stand and walk by myself for 5 minutes, with or without medication.
I have Parkinson's disease at stage III, affecting my balance.
I am between 50 and 85 years old.
See 1 more

Timeline

Screening

Participants are screened for eligibility to participate in the trial

1 week
1 visit (in-person)

Baseline Assessment

Participants undergo baseline assessments including postural sway, gait spatiotemporal parameters, and EEG spectral ratio

1 week
2 assessments (in-person)

Treatment

Participants receive 1-week postural training using Segway to provide augmented proprioceptive and visuospatial information

1 week
Multiple sessions (in-person)

Post-Treatment Assessment

Participants are assessed for changes in postural sway, gait spatiotemporal parameters, and EEG spectral ratio

1 week
1 assessment (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 week

Treatment Details

Interventions

  • Sensory-Augmented Postural Training
Trial Overview The study tests the safety and effectiveness of sensory-augmented postural training using a Segway to improve balance in Parkinson's patients by providing continuous proprioceptive (body position sense) and visuospatial (space around us) feedback during exercises.
Participant Groups
1Treatment groups
Experimental Treatment
Group I: PD - individuals with Parkinson Disease, either male or femaleExperimental Treatment1 Intervention
Individuals, aged 50-85, with a clinical diagnosis of idiopathic Parkinson Disease, either male or female, with moderate disease stage presenting balance alterations (Hoehn or Yahr stage III)

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Texas Southwestern Medical Center

Lead Sponsor

Trials
1,102
Recruited
1,077,000+

Findings from Research

Perturbation-based balance training (PBT) shows promise in improving postural control and gait in people with Parkinson's disease, potentially reducing falls and the severity of symptoms, based on a systematic review of 11 studies.
Despite the positive findings, the overall quality of evidence was downgraded due to publication bias and methodological limitations, suggesting that further high-quality research is needed to confirm these benefits.
A systematic review on the effectiveness of perturbation-based balance training in postural control and gait in Parkinson's disease.Coelho, DB., de Oliveira, CEN., Guimarães, MVC., et al.[2022]
A pilot study involving 33 patients with Parkinson's disease showed that a balance training program using augmented visual feedback (VFT) was feasible and safe, with no adverse events reported during the five-week training.
While VFT showed favorable trends in improving balance measures compared to conventional training, it did not demonstrate statistically significant superiority in the primary outcome, the Functional Reach test, indicating that further optimization may be needed to enhance its effectiveness.
Effects of augmented visual feedback during balance training in Parkinson's disease: a pilot randomized clinical trial.van den Heuvel, MR., Kwakkel, G., Beek, PJ., et al.[2014]
A pilot study involving 18 participants with Parkinson's disease showed that using real-time multimodal sensory feedback (MMSF) during stepping exercises significantly improved backward stride length over 12 and 18 weeks, suggesting enhanced gait safety and reduced fall risk.
Participants using MMSF reported greater self-perceived improvements in gait and quality of life, indicating that MMSF not only aids in physical performance but also positively impacts daily living and overall well-being.
Use of real-time multimodal sensory feedback home program improved backward stride and retention for people with Parkinson Disease: A pilot study.Winkler, P., DeMarch, E., Campbell, H., et al.[2022]

References

A systematic review on the effectiveness of perturbation-based balance training in postural control and gait in Parkinson's disease. [2022]
Effects of augmented visual feedback during balance training in Parkinson's disease: a pilot randomized clinical trial. [2014]
Use of real-time multimodal sensory feedback home program improved backward stride and retention for people with Parkinson Disease: A pilot study. [2022]
Proprioceptive Focal Stimulation (Equistasi®) for gait and postural balance rehabilitation in patients with Parkinson's disease: A systematic review. [2023]
Postural reactions to neck vibration in Parkinson's disease. [2008]
Virtual sensory feedback for gait improvement in neurological patients. [2021]
A wearable proprioceptive stabilizer (Equistasi®) for rehabilitation of postural instability in Parkinson's disease: a phase II randomized double-blind, double-dummy, controlled study. [2018]
Effects of virtual reality-augmented balance training on sensory organization and attentional demand for postural control in people with Parkinson disease: a randomized controlled trial. [2022]
Focal Vibration Training (Equistasi®) to Improve Posture Stability. A Retrospective Study in Parkinson's Disease. [2020]
Sensorimotor integration training in Parkinson`s disease. [2021]
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security