← Back to Search

Movement Task Facilitation for Parkinson's Disease

N/A

Recruiting

Research Sponsored by University of California, Los Angeles

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosis of idiopathic Parkinson's disease based on presence of at least 2 cardinal PD features (tremor, rigidity, or bradykinesia)

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline

Awards & highlights

Study Summary

This trial will help researchers understand how different types of cues can help patients with Parkinson's disease move more normally, which may lead to new treatments.

Who is the study for?

This trial is for people with advanced Parkinson's disease who are already scheduled for deep brain stimulation surgery. They should be able to cooperate during an awake procedure and have symptoms that improve with L-dopa or have a medication-refractory disabling tremor. Participants must not have cognitive impairments, psychiatric diseases, or medical conditions that rule out surgery.Check my eligibility

What is being tested?

The study aims to understand how certain stimuli facilitate movement in Parkinson's patients by recording brain activity during DBS surgery. Patients will perform movement tasks while awake, which could help identify new targets for treating symptoms unresponsive to current therapies.See study design

What are the potential side effects?

Since the study involves standard clinical procedures of DBS surgery and no additional drugs, side effects are primarily related to the surgical process itself such as discomfort from being awake during the operation and potential risks associated with any surgical intervention.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have Parkinson's with symptoms like tremor, stiffness, or slow movement.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Frontal and parietal electrocorticography

Globus pallidus internus local field potentials

Trial Design

1Treatment groups

Experimental Treatment

Group I: Parkinson disease patientsExperimental Treatment1 Intervention

Parkinson disease patients undergoing DBS Surgery of the Globus Pallidus Internus (GPi) for clinical indications

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)NIH

1,341 Previous Clinical Trials

650,099 Total Patients Enrolled

University of California, Los AngelesLead Sponsor

1,533 Previous Clinical Trials

10,265,528 Total Patients Enrolled

Media Library

Movement task Clinical Trial Eligibility Overview. Trial Name: NCT05166655 — N/A

Parkinson's Disease Research Study Groups: Parkinson disease patients

Parkinson's Disease Clinical Trial 2023: Movement task Highlights & Side Effects. Trial Name: NCT05166655 — N/A

Movement task 2023 Treatment Timeline for Medical Study. Trial Name: NCT05166655 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any current openings for participation in this clinical experiment?

"Based on information from clinicaltrials.gov, this particular trial is no longer recruiting patients. Initially posted on March 3rd 2022 and last updated on July 5th of the same year, 488 other studies are available for potential participants right now."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

DBS Recordings to Characterize Movement Facilitation in Parkinson's Disease

Kathryn A. Cross, MD, PhD 2022. "DBS Recordings to Characterize Movement Facilitation in Parkinson's Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05166655.

All > Dbs > Parkinson Disease