Prehabilitation for Pancreatic Cancer

Overseen By James M Lindberg, MD

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of Massachusetts, Worcester

Disqualifiers: Pregnant, Prisoner, Cognitive impairment, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

20 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this clinical study is to test whether a structured prehabilitation program can be successfully used by adults with pancreatic cancer who are receiving chemotherapy before planned surgery. Prehabilitation is a program designed to improve a person's physical fitness, nutrition, and symptom control before surgery.

The study's main hypothesis is that patients with pancreatic cancer can take part in and adhere to a multimodal prehabilitation program during chemotherapy, and that doing so may improve physical function, patient experience, and early recovery after surgery.

Who Is on the Research Team?

James M Lindberg, MD

Principal Investigator

UMass Memorial Health

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 18 years old or older.

I have been diagnosed with pancreatic ductal adenocarcinoma.

I am scheduled to have chemotherapy before my surgery.

Exclusion Criteria

Pregnant

Contraindications to physical activity, including unstable cardiac disease, severe pulmonary disease, or recent myocardial infarction

I am younger than 18 years old.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Prehabilitation

Participants engage in a structured prehabilitation program during neoadjuvant chemotherapy to improve physical fitness, nutrition, and symptom control before surgery

3-6 months

Regular visits for assessments and program adherence checks

Surgery

Participants undergo planned pancreatic cancer surgery following the prehabilitation program

1 week

Hospital stay for surgery and immediate recovery

Follow-up

Participants are monitored for safety, effectiveness, and recovery after surgery

Up to 1 year

Postoperative assessments at 1 month and up to 1 year

What Are the Treatments Tested in This Trial?

Interventions

• Multimodal Prehabilitation

How Is the Trial Designed?

Group I: Multimodal Prehabilitation Program Experimental Treatment 1 Intervention

Participants in this single-arm study will receive a structured prehabilitation program during neoadjuvant chemotherapy prior to planned pancreatic cancer surgery.

Who Is Running the Clinical Trial?

University of Massachusetts, Worcester

Lead Sponsor

Trials

372

Recruited

998,000+

Pancreatic Cancer Alliance

Collaborator