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Green LED for Osteoarthritis

N/A

Waitlist Available

Led By Karim Mukhida, MD, PhD

Research Sponsored by Nova Scotia Health Authority

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Moderate to severe pain, as defined by an average 7-day pain score of greater than 4.0 on an 11-point numerical rating scale for pain intensity (NRS-PI)

Osteoarthritis of the knee according to American College of Rheumatology criteria: Knee pain with 3 of the following: age >50 years, stiffness less than 30 min, crepitus, bony tenderness, bony enlargement, no palpable warmth

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 weeks

Awards & highlights

Study Summary

This trial aims to investigate whether green light therapy can help reduce joint pain in people with knee osteoarthritis. Participants will be asked to track their pain levels for 4 weeks before starting the light

Who is the study for?

This trial is for adults with knee osteoarthritis who can read and write English, have moderate to severe pain, and stable medication use. They should be able to follow the study protocol and give informed consent. People with unstable housing or inability to attend visits are excluded.Check my eligibility

What is being tested?

The trial is testing if green LED light therapy reduces pain in knee osteoarthritis patients compared to white LED light. Participants will first use white LED at home for 10 weeks, then after a break, switch to green LED for another 10 weeks while keeping a pain diary.See study design

What are the potential side effects?

While not explicitly mentioned, potential side effects of light therapy may include eye strain or headache due to exposure; however, since it's non-pharmacological treatment, adverse reactions are expected to be minimal.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

My average pain level is more than 4 out of 10 over the last week.

Select...

I have knee pain, am over 50, and my knee is stiff, makes noise, feels tender or enlarged without being warm.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pain Score Diary

Secondary outcome measures

Brief Pain Inventory Short Form

Global impression of change and satisfaction

Western Ontario and McMaster University Arthritis Index (WOMAC)

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Green LEDExperimental Treatment2 Interventions

Participants will be asked to use green LEDs for 1-2 hours/day in a dark room in their home.

Group II: White LEDPlacebo Group2 Interventions

Participants will be asked to use white LEDs for 1-2 hours/day in a dark room in their home.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Green LED light

2017

N/A

~60

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Nova Scotia Health AuthorityLead Sponsor

258 Previous Clinical Trials

83,808 Total Patients Enrolled

10 Trials studying Osteoarthritis

547 Patients Enrolled for Osteoarthritis

Karim Mukhida, MD, PhDPrincipal InvestigatorNova Scotia Health Authority

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are individuals aged 60 and above eligible for enrollment in this study?

"Individuals aged 18 to less than 80 years are eligible for enrollment in this research."

Answered by AI

Is the enrollment for this medical study currently accepting new participants?

"According to clinicaltrials.gov, this specific research endeavor is not presently seeking volunteers. While the trial was initially shared on 2/15/2023 and last updated on 2/9/2024, there are currently 663 alternative studies actively recruiting participants."

Answered by AI

Which specific criteria determine the eligibility of individuals to participate in this study?

"This research seeks 46 individuals aged between 18 and 80 with a current diagnosis of osteoarthritis, specifically in the knee as per the American College of Rheumatology guidelines. Participants must experience knee pain along with specific criteria such as age over 50 years, limited stiffness duration, crepitus, bony tenderness or enlargement without warmth palpation, and moderate to severe pain levels exceeding a score of 4.0 on an 11-point numerical rating scale for pain intensity. Other requirements include fluency in English reading and writing skills, stable medication use for at least two weeks prior to enrollment for any indication, capability"

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Analgesic Potential of Light Therapy in Knee Osteoarthritis

Karim Mukhida 2023. "Analgesic Potential of Light Therapy in Knee Osteoarthritis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05398666.

All > Knee Osteoarthritis