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Inpatient vs Outpatient Knee Surgery for Osteoarthritis

N/A

Recruiting

Led By Brent Lanting, MD, FRCSC

Research Sponsored by Lawson Health Research Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Booked for primary unilateral total knee arthroplasty

Osteoarthritis of the knee

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial is comparing two types of knee surgery in terms of patient satisfaction and cost.

Who is the study for?

This trial is for adults with knee osteoarthritis who are scheduled for primary unilateral total knee replacement, can read and understand English, have a phone, plan to go home after surgery, and have someone to accompany them. It's not for those with cognitive issues or severe health problems (ASA score ≤4).Check my eligibility

What is being tested?

The study compares two approaches: standard inpatient total knee replacement requiring an overnight hospital stay versus same-day discharge outpatient surgery. It will evaluate patient satisfaction and the costs involved from various perspectives.See study design

What are the potential side effects?

While not explicitly listed here, potential side effects may include typical risks associated with knee replacement surgeries such as pain, swelling, infection risk at the surgical site, blood clots, or complications related to anesthesia.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am scheduled for a first-time knee replacement on one side.

Select...

I have osteoarthritis in my knee.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Indirect and direct costs of treatment

Rate of early complications and adverse events

Standardized measure of health outcome (EQ-5D)

Secondary outcome measures

Knee Society Score

Oxford Knee Score - English for Canada

Pain Numeric Rating Scale

+3 more

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: OutpatientExperimental Treatment1 Intervention

Patients in the outpatient group (same day discharge following TKA) are discharged the same day following surgery. All patients are required to meet the discharge criteria to be sent home (i.e., capable of using crutches, relatively free of pain, free of nausea and vomiting, free of excess bleeding, alert and oriented, given take-home medications, and in the company of a caregiver).

Group II: InpatientActive Control1 Intervention

Patients in the inpatient group (following day discharge following TKA) stay in the hospital overnight and then are discharged home the next day. All patients are required to meet the discharge criteria to be sent home (i.e., capable of using crutches, relatively free of pain, free of nausea and vomiting, free of excess bleeding, alert and oriented, given take-home medications, and in the company of a caregiver).

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Outpatient

2015

N/A

~1060

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Lawson Health Research InstituteLead Sponsor

659 Previous Clinical Trials

413,432 Total Patients Enrolled

22 Trials studying Osteoarthritis

5,567 Patients Enrolled for Osteoarthritis

Brent Lanting, MD, FRCSCPrincipal InvestigatorLondon Health Sciences Centre

1 Previous Clinical Trials

558 Total Patients Enrolled

1 Trials studying Osteoarthritis

558 Patients Enrolled for Osteoarthritis

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants currently being enrolled for this research endeavor?

"The information hosted on clinicaltrials.gov indicates that this medical trial is currently recruiting. It was initially published on October 22nd 2020, and the last update to it occurred a year later in 2021."

Answered by AI

How many participants is the research team admitting to this trial?

"Affirmative. The public records on clinicaltrials.gov clearly demonstrate that this healthcare research, with a commencement date of October 22nd 2020, is actively enrolling patients. Presently they are searching for 300 subjects to be recruited from one medical centre."

Answered by AI

What are the objectives of this clinical endeavor?

"The primary objective of this one year clinical trial is to determine the associated economic costs. Secondary metrics include the Knee Society Score (which measures functional capacity from 0-100), Caregiver Strain Index (a measure between stress levels of 0-13) and the Caregiver Assistance Scale, which assesses the amount of help needed with 17 questions scored on a 7 point Likert scale ranging from none to a lot; higher scores indicate greater need for assistance."

Answered by AI

Recent research and studies

Journal of Bone and Joint SurgeryJournal

Impact of the Economic Downturn on Total Joint Replacement Demand in the United States

Kurtz, Steven M., Kevin L. Ong, Edmund Lau, and Kevin J. Bozic. 2014. “Impact of the Economic Downturn on Total Joint Replacement Demand in the United States”. Journal of Bone and Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.m.00285.

Journal of Bone and Joint SurgeryJournal

Hospital Discharge Within 2 Days Following Total Hip or Knee Arthroplasty Does Not Increase Major-complication and Readmission Rates

Sutton, J. Carl, John Antoniou, Laura M. Epure, Olga L. Huk, David J. Zukor, and Stephane G. Bergeron. 2016. “Hospital Discharge Within 2 Days Following Total Hip or Knee Arthroplasty Does Not Increase Major-complication and Readmission Rates”. Journal of Bone and Joint Surgery. Ovid Technologies (Wolters Kluwer Health). doi:10.2106/jbjs.15.01109.

HSS Journal ®Journal

Outpatient Surgery as a Means of Cost Reduction in Total Hip Arthroplasty: A Case-control Study

Aynardi, Michael, Zachary Post, Alvin Ong, Fabio Orozco, and Dean C. Sukin. 2014. “Outpatient Surgery as a Means of Cost Reduction in Total Hip Arthroplasty: A Case-control Study”. HSS Journal ®. SAGE Publications. doi:10.1007/s11420-014-9401-0.

Clinical Orthopaedics and Related Research®Journal