Opioid Stewardship Intervention for Opioid Prescribing

Not yet recruiting at 1 trial location
JS
MH
Overseen ByMeaghan Hazelet
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of North Carolina, Chapel Hill
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The goal of this stepped-wedge cluster randomized trial is to evaluate whether an opioid stewardship intervention improves post-operative opioid prescribing practices. Participants will include surgeon champions and identified change team members (e.g., pharmacists, hospitalists, nurses, advanced practice providers, anesthesiologists, etc.) and patient representatives at designated hospital sites in North Carolina.

The main questions it aims to answer are:

I. Does the intervention reduce postoperative opioid prescribing behavior at the surgeon and hospital level? II. Is the intervention acceptable, feasible, and effective for implementation among participating hospitals?

Researchers will compare opioid prescribing and implementation outcomes across sites before and after implementation using a stepped-wedge cluster randomized design, in which sites are randomly assigned to different intervention start times.

Participants will attend educational sessions delivered, introduce the Standard Opioid Prescribing (SOPS) Toolkit into their clinical practice, review benchmarked, deidentified opioid prescribing performance reports that use administrative claims data (secondary data source, data not collected or shared between hospitals), and complete surveys assessing intervention acceptability, feasibility, and effectiveness. Preliminary effectiveness will be assessed through reduction of opioid prescriptions using administrative claims data.

Who Is on the Research Team?

JS

Jessica Schumacher, PhD

Principal Investigator

University of North Carolina, Chapel Hill

Are You a Good Fit for This Trial?

Inclusion Criteria

Surgeon champions and identified change team members must be currently practicing at one of the sites participating in this study
I am at least 18 and had continuous insurance before and after my surgery.
I speak English and was prescribed opioids after a qualifying general surgery.

Exclusion Criteria

Patients with an opioid fill 6 months before the procedure
I had a major surgery during my hospital stay that needs extra pain management.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Control Phase

Hospitals continue opioid prescribing according to existing local practices without receiving any components of the opioid stewardship intervention.

Varies based on randomization

Intervention Phase

Hospitals implement a multi-component opioid stewardship intervention, including the SOPS Toolkit, educational sessions, and performance reports.

10 weeks
Educational sessions and performance reviews

Follow-up

Participants are monitored for the effectiveness of the intervention through surveys and interviews assessing acceptability, feasibility, and effectiveness.

6 months after intervention completion

What Are the Treatments Tested in This Trial?

Interventions

  • Opioid Stewardship Intervention

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Usual Care (Control Period)Experimental Treatment1 Intervention
Group II: Opioid Stewardship Intervention (Intervention Period)Experimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of North Carolina, Chapel Hill

Lead Sponsor

Trials
1,588
Recruited
4,364,000+