← Back to Search

Transcranial Magnetic Stimulation + Habit Training for Compulsive Behavior

N/A
Recruiting
Led By Rebecca B Price, PhD
Research Sponsored by Rebecca Price
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between the ages of 18 and 60 years
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 90min-1 week
Awards & highlights

Study Summary

This trial will help to identify which part of the brain is linked with compulsive behaviors, in order to develop better treatments for those with compulsions.

Who is the study for?
This trial is for adults aged 18-60 with compulsive behaviors, who can stay in Pittsburgh for at least 5 weeks. Participants must be okay with being videotaped during interviews and not have metal implants (except dental fillings), history of brain injury/surgery, or conditions affecting seizure risk like epilepsy.Check my eligibility
What is being tested?
The study tests if brain stimulation (Theta Burst Stimulation) combined with a computer task to practice habit control can influence compulsive behaviors. Some participants will receive real treatment while others get sham (fake) versions to compare effects.See study design
What are the potential side effects?
Transcranial Magnetic Stimulation may cause discomfort at the stimulation site, headache, lightheadedness, or seizures in very rare cases. The side effects are generally mild and temporary.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am between 18 and 60 years old.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~90min-1 week
This trial's timeline: 3 weeks for screening, Varies for treatment, and 90min-1 week for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Secondary outcome measures
Brain activation in target region
Duration of compulsive behaviors in response to laboratory triggers
Effort to resist compulsive behaviors in response to laboratory triggers
+5 more

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: cTBS + Habit Override TrainingExperimental Treatment2 Interventions
Transcranial Magnetic Stimulation delivered in a continuous Theta Burst Stimulation (cTBS) pattern, paired with Habit Override Training.
Group II: Sham TBS + Habit Override TrainingActive Control2 Interventions
Sham Transcranial Magnetic Stimulation, paired with Habit Override Training.
Group III: cTBS + Sham TrainingActive Control2 Interventions
Transcranial Magnetic Stimulation delivered in a continuous Theta Burst Stimulation (cTBS) pattern, paired with Sham Training.
Group IV: Sham TBS + Sham TrainingPlacebo Group2 Interventions
Sham Transcranial Magnetic Stimulation, paired with Sham Training.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Transcranial Magnetic Stimulation
2011
Completed Phase 4
~710
Habit Override Practice
2017
N/A
~80

Find a Location

Who is running the clinical trial?

Rebecca PriceLead Sponsor
6 Previous Clinical Trials
468 Total Patients Enrolled
National Institute of Mental Health (NIMH)NIH
2,777 Previous Clinical Trials
2,673,810 Total Patients Enrolled
65 Trials studying Obsessive-Compulsive Disorder
13,781 Patients Enrolled for Obsessive-Compulsive Disorder
Rebecca B Price, PhDPrincipal InvestigatorUniversity of Pittsburgh
1 Previous Clinical Trials
200 Total Patients Enrolled

Media Library

Habit Override Practice Clinical Trial Eligibility Overview. Trial Name: NCT04580043 — N/A
Obsessive-Compulsive Disorder Research Study Groups: Sham TBS + Habit Override Training, cTBS + Sham Training, Sham TBS + Sham Training, cTBS + Habit Override Training
Obsessive-Compulsive Disorder Clinical Trial 2023: Habit Override Practice Highlights & Side Effects. Trial Name: NCT04580043 — N/A
Habit Override Practice 2023 Treatment Timeline for Medical Study. Trial Name: NCT04580043 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there an opportunity to partake in this research project?

"This research initiative is open to a cohort of 200 individuals aged 18-60 that demonstrate compulsive behaviors. To be eligible, they must also agree to video taping and confirm their residence in the Pittsburgh area for at least 5 weeks."

Answered by AI

How many volunteers are currently participating in this experiment?

"Confirmed. Clinicaltrials.gov displays that the research was first announced on December 28th 2020, and is presently recruiting participants. 200 volunteers are needed from 1 site to take part in the study."

Answered by AI

Are recruitment efforts still ongoing for this research project?

"Indeed, clinicaltrials.gov states that this trial is currently accepting patients after being initially posted on December 28th 2020 and updated most recently on August 14th 2022. 200 participants are needed at a single medical site."

Answered by AI

Is this experiment recruiting senior citizens?

"This trial necessitates that any patient enrolling is between 18 and 60 years old. Meanwhile, there are other studies targeting minors as well as those over 65 years of age with 26 trials and 68 trials respectively."

Answered by AI

Who else is applying?

What state do they live in?
Pennsylvania
California
What site did they apply to?
Western Psychiatric Institute and Clinic
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
0
3+
~70 spots leftby Jan 2026