Behavioral Intervention for Chronic Disease Prevention

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: City of Hope Medical Center

Disqualifiers: Under 18, Can't do physical activity

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

347 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial tests the EML Program, which offers free classes on healthy eating and physical activity to underserved communities. The goal is to help participants make better lifestyle choices and reduce their risk of chronic diseases.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What data supports the effectiveness of the Eat, Move, Live Program treatment for chronic disease prevention?

Research shows that programs focusing on improving diet and physical activity, like the Eat, Move, Live Program, can lead to healthier eating habits and increased physical activity, which are important for preventing chronic diseases. For example, a study with older adults found that a similar program improved their diet and physical activity levels, which are key factors in preventing chronic illnesses. ^{1 2 3 4 5}

Is the Eat, Move, Live Program safe for humans?

The studies reviewed suggest that behavioral interventions like the Eat, Move, Live Program, which focus on improving diet and physical activity, are generally safe for humans. Participants in these programs showed improvements in health behaviors without reported adverse effects. ^{1 6 7 8 9}

How is the Eat, Move, Live Program treatment different from other treatments for chronic disease prevention?

The Eat, Move, Live Program is unique because it focuses on small, sustainable changes in daily habits related to food choices and physical activity, rather than drastic lifestyle overhauls. It includes practical components like grocery store tours for better food selection and basic cooking skills, which are not typically emphasized in other chronic disease prevention programs. ^{1 10 11 12 13}

Research Team

Victoria L Seewaldt

Principal Investigator

City of Hope Medical Center

Eligibility Criteria

The Eat, Move, Live Program is for adults over 18 from underserved communities who can speak and understand English or Spanish. It's designed to help reduce cancer and chronic disease risk by teaching healthy lifestyle habits. Participants must be able to engage in physical activity and agree to group consent.

Inclusion Criteria

Age over 18

You agree to group consent at week 1.\n

You can speak and understand English and/or Spanish.

Exclusion Criteria

You are not able to participate in physical activity.

Don't agree to group consent at week 1

Age younger than 18

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants attend EML program sessions weekly for 12 weeks including an educational session on chronic disease risk reduction via nutrition and physical activity, a physical activity session, and a cooking/taste test demonstration.

12 weeks

Follow-up

Participants are monitored for changes in body measurements, biomarkers, and attitudes and behaviors after the treatment phase.

4 weeks

Treatment Details

Interventions

• Eat, Move, Live Program

Trial Overview This trial tests the EML Program's effectiveness in promoting better nutrition and increasing physical activity. The program includes culturally tailored educational sessions on diet, exercise, food label reading, recipe modification, budget-friendly healthy eating, and chronic disease prevention.

Participant Groups

Group I: Supportive care (EML program) Experimental Treatment 2 Interventions

Participants attend EML program sessions weekly for 12 weeks including an educational session chronic disease risk reduction via nutrition and physical activity, a physical activity session, and a cooking/taste test demonstration.

Who Is Running the Clinical Trial?

City of Hope Medical Center

Lead Sponsor

Trials

614

Recruited

1,924,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Findings from Research

Comprehensive lifestyle behavior change programs that focus on diet and physical activity have shown promise in altering the progression of diabetes, highlighting their potential efficacy in weight loss and diabetes management.

The report discusses challenges related to the sustainability and feasibility of these programs, indicating that while they can be effective, maintaining long-term behavior change remains a significant hurdle.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of lifestyle behavior change programs in diabetes. Venditti, EM.[2022]

References

1. United States pubmed.ncbi.nlm.nih.gov

Wise Choices: Nutrition and Exercise for Older Adults: A Community-Based Health Promotion Intervention. [2019]

2. United States pubmed.ncbi.nlm.nih.gov

A randomized trial of a tailored, self-help dietary intervention: the Puget Sound Eating Patterns study. [2022]

3. Ireland pubmed.ncbi.nlm.nih.gov

Optimizing acceptability and feasibility of an evidence-based behavioral intervention for obese adults with obesity-related co-morbidities or additional risk factors for co-morbidities: an open-pilot intervention study in secondary care. [2022]

4. United States pubmed.ncbi.nlm.nih.gov

Efficacy of lifestyle behavior change programs in diabetes. [2022]

5. Canada pubmed.ncbi.nlm.nih.gov

Multicomponent mHealth Intervention for Large, Sustained Change in Multiple Diet and Activity Risk Behaviors: The Make Better Choices 2 Randomized Controlled Trial. [2023]

6. England pubmed.ncbi.nlm.nih.gov

A comparative effectiveness education trial for lifestyle health behavior change in African Americans. [2022]

7. United States pubmed.ncbi.nlm.nih.gov

Small changes in dietary sugar and physical activity as an approach to preventing excessive weight gain: the America on the Move family study. [2019]

8. United States pubmed.ncbi.nlm.nih.gov

Interventions for improving nutrition and physical activity behaviors in adult African American populations: a systematic review, January 2000 through December 2011. [2022]

9. United States pubmed.ncbi.nlm.nih.gov

Expanding the criteria for defining success when evaluating weight loss intervention programs. [2019]

10. United States pubmed.ncbi.nlm.nih.gov

Increasing healthy eating vs. reducing high energy-dense foods to treat pediatric obesity. [2022]

11. Netherlands pubmed.ncbi.nlm.nih.gov

A review of eHealth interventions for physical activity and dietary behavior change. [2022]

12. Switzerland pubmed.ncbi.nlm.nih.gov

Evaluation of the Small Changes, Healthy Habits Pilot Program: Its Influence on Healthy Eating and Physical Activity Behaviors of Adults in Louisiana. [2023]

13. Australia pubmed.ncbi.nlm.nih.gov

Assessing the real world effectiveness of the Healthy Eating Activity and Lifestyle (HEAL) program. [2018]