Behavioral Intervention for Chronic Disease Prevention

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: City of Hope Medical Center

Disqualifiers: Under 18, Can't do physical activity

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 weeks

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to test the Eat, Move, Live (EML) Program, which seeks to reduce the risk of chronic diseases like cancer by promoting healthier lifestyle habits. Designed for underserved communities, it includes sessions on nutrition, physical activity, and healthy cooking. Participants will learn to eat healthily on a budget, understand food labels, and modify recipes for better health. This trial suits adults who speak English or Spanish and are willing to engage in physical activities. As an unphased trial, it offers a unique opportunity for participants to contribute to valuable research that could enhance community health.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that the Eat, Move, Live Program is safe for participants?

Research shows that the Eat, Move, Live (EML) Program is safe for participants. This program aims to improve diet and physical activity, which most people can handle well. Studies on similar programs, such as "Eat Smart, Move More, Weigh Less," have shown positive results, including weight loss, without major side effects. This evidence suggests that joining a lifestyle change program like EML is unlikely to cause harm. Instead, it promotes healthy habits that can help lower the risk of chronic diseases. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Eat, Move, Live (EML) Program because it offers a holistic approach to preventing chronic diseases, focusing on lifestyle changes rather than medication. Unlike traditional treatments that might involve pharmaceuticals, the EML Program combines weekly educational sessions on nutrition and physical activity with hands-on experiences like cooking and taste tests. This method empowers participants to actively reduce their disease risk through sustainable lifestyle changes, potentially leading to long-lasting health benefits.

What evidence suggests that the Eat, Move, Live Program is effective for reducing the risk of chronic diseases?

Research shows that the Eat, Move, Live (EML) Program, which participants in this trial will attend, can help lower the risk of long-term illnesses. Studies have found that this program encourages healthier lifestyle choices, such as eating better and being more active. Participants in similar programs have lost weight and improved their blood sugar levels, which is important for preventing diseases like diabetes. The EML Program offers culturally relevant education, helping participants learn to read food labels, cook healthy meals, and stay active. By focusing on simple, everyday changes, it aims to reduce the risk of chronic diseases in communities that need it most. ^{1 2 3 6 7}

Who Is on the Research Team?

Victoria L Seewaldt

Principal Investigator

City of Hope Medical Center

Are You a Good Fit for This Trial?

The Eat, Move, Live Program is for adults over 18 from underserved communities who can speak and understand English or Spanish. It's designed to help reduce cancer and chronic disease risk by teaching healthy lifestyle habits. Participants must be able to engage in physical activity and agree to group consent.

Inclusion Criteria

You agree to group consent at week 1.\n

You can speak and understand English and/or Spanish.

Exclusion Criteria

You are not able to participate in physical activity.

Don't agree to group consent at week 1

Age younger than 18

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants attend EML program sessions weekly for 12 weeks including an educational session on chronic disease risk reduction via nutrition and physical activity, a physical activity session, and a cooking/taste test demonstration.

12 weeks

Follow-up

Participants are monitored for changes in body measurements, biomarkers, and attitudes and behaviors after the treatment phase.

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Eat, Move, Live Program

Trial Overview This trial tests the EML Program's effectiveness in promoting better nutrition and increasing physical activity. The program includes culturally tailored educational sessions on diet, exercise, food label reading, recipe modification, budget-friendly healthy eating, and chronic disease prevention.

How Is the Trial Designed?

Group I: Supportive care (EML program) Experimental Treatment 2 Interventions

Participants attend EML program sessions weekly for 12 weeks including an educational session chronic disease risk reduction via nutrition and physical activity, a physical activity session, and a cooking/taste test demonstration.

Who Is Running the Clinical Trial?

City of Hope Medical Center

Lead Sponsor

Trials

614

Recruited

1,924,000+

National Cancer Institute (NCI)

Collaborator

Trials

14,080

Recruited

41,180,000+

Published Research Related to This Trial

Comprehensive lifestyle behavior change programs that focus on diet and physical activity have shown promise in altering the progression of diabetes, highlighting their potential efficacy in weight loss and diabetes management.

The report discusses challenges related to the sustainability and feasibility of these programs, indicating that while they can be effective, maintaining long-term behavior change remains a significant hurdle.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of lifestyle behavior change programs in diabetes. Venditti, EM.[2022]

Citations

1. sciencedirect.com sciencedirect.com/science/article/pii/S104620232400207X

Digital Intervention for behaviouR changE and Chronic ... This study will inform the development and implementation of interventions using web-based wellness platforms and personalized digital interventions.

2. clinicaltrials.gov clinicaltrials.gov/study/NCT02513407

Eat, Move, Live Intervention in Reducing Chronic Disease ... This randomized pilot research trial studies how well Eat, Move, Live (EML) works in reducing chronic disease risk in medically vulnerable communities.

3. clinicaltrials.gov clinicaltrials.gov/study/NCT05414396

Eat, Move, Live Program for the Reduction of Cancer and ... This clinical trial tests the Eat, Move, Live (EML) Program in reducing the risk of chronic diseases among underserved communities by improving healthy ...

4. mdpi.com mdpi.com/2673-4540/6/5/42

Plan, Track, and Live Mindfully: Insights from the Eat Smart ... The Centers for Disease Control and Prevention (CDC) recommends a modest weight loss of 5–7%, a reduction in A1C by 0.2%, and at least 150 min of physical ...

5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC1829349/

Eat Better & Move More: A Community-Based Program ... This easy-to-implement program improves diets and activity levels. Local providers should offer more such programs with the goal of enabling older Americans.

6. ncoa.org ncoa.org/article/evidence-based-program-eat-smart-move-more-weigh-less/

Eat Smart, Move More, Weigh Less Participants who completed the program lost significantly more weight than those in the wait-list control group and had a greater reduction in ...

7. cdc.gov cdc.gov/pcd/issues/2011/jul/pdf/10_0160.pdf

Effects of a Behavior-Based Weight Management Program ... Eat Smart, Move More, Weigh Less (ESMMWL) is an adult weight management program developed in response to North Carolina Obesity Plan ...