Blood Sample Collection for Myasthenia Gravis
(EXPLORE-MG2 Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to gather information and samples from people with myasthenia gravis (MG), a condition that causes muscle weakness. The goal is to build a resource for researchers to better understand MG and improve future treatments. Participants will be recruited from outpatient clinics and must have been diagnosed with MG, showing specific symptoms or test results linked to the disease. This trial is ideal for those diagnosed within the last two years or those with specific antibodies or thymoma-related MG. As an unphased trial, it offers participants the opportunity to contribute to foundational research that could lead to breakthroughs in MG treatment.
Do I have to stop taking my current medications for the trial?
The trial information does not specify if you need to stop taking your current medications. It mainly focuses on collecting blood samples and data for myasthenia gravis research.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to better understand the characteristics and outcomes of Myasthenia Gravis (MG) among neurological outpatients. Unlike traditional studies that focus on specific drugs or therapies, this trial seeks to gather comprehensive data from patients directly within clinical settings. By observing real-world patient experiences and responses, the trial could lead to more personalized and effective treatment strategies for MG in the future.
Who Is on the Research Team?
Richard Nowak, MD
Principal Investigator
Yale University
Vern Juel, MD
Principal Investigator
Duke University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Data and Sample Collection
Comprehensive clinical phenotyping linked to bio-specimen collection to understand disease characteristics
Follow-up
Participants are monitored for safety and effectiveness after data and sample collection
What Are the Treatments Tested in This Trial?
Interventions
- Blood sample
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants in this group will be recruited from the outpatient clinical population at MGNet participating sites. Treating physicians will make the initial determination of patients' potential eligibility to participate in the study.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
National Center for Advancing Translational Sciences (NCATS)
Collaborator
National Institute of Neurological Disorders and Stroke (NINDS)
Collaborator
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