Strength Training for Muscle Mass in GLP-1 Users
(STRONG-GLP Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
GLP-1 medication is being prescribed for weight loss. However, GLP-1 medication may adversely affect muscle mass and muscle function. Moreover, any loss of muscle mass or muscle function with GLP-1 treatment may impair balance and increase fall risk. This is a particular concern among older adults already susceptible to the common muscle strength and muscle function loss with age, yet there is little evidence among this population. This study will address a gap in knowledge regarding the effects of GLP-1 treatment on muscle mass, muscle function, and balance/fall risk among adults age 50 and older.
Who Is on the Research Team?
Kevin Davy
Principal Investigator
Virginia Polytechnic Institute and State University
Are You a Good Fit for This Trial?
This trial is for adults aged 50 and older who weigh less than 300 pounds, have been taking GLP-1 medication (Weygovy or Zepbound) for a month or less, and pass a health and exercise readiness screening. It's focused on those concerned about muscle mass and function as they age.Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- GLP-1 Agonist
- Strength Training
Trial Overview
The study examines how strength training affects muscle in people using GLP-1 medications for weight loss. Participants will either wait before starting strength training or begin it immediately to see the impact on muscle mass, function, and balance.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Participants will have no strength training intervention for 14 weeks. Participants will be offered the same 14-week strength training program after the initial 14 weeks.
Participants will undergo strength training 3 times per week for 14 weeks.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Virginia Polytechnic Institute and State University
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.