120 Participants Needed

Mindfulness-Based Intervention for Stress

(4SITE Trial)

Recruiting at 3 trial locations
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Colorado State University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to find effective ways to reduce depression, anxiety, and stress in college students. It compares two mindfulness programs, Learning to BREATHE and Learning to BREATHE Plus, with a health education program to determine which best helps students manage stress. The trial seeks college students who feel stressed and can attend in-person sessions next semester. Participants need a smartphone to join.

As an unphased trial, this study offers students the opportunity to explore innovative mindfulness techniques to enhance their well-being.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It focuses on mindfulness and stress reduction for college students.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that the Learning to BREATHE (L2B) program is safe and easy to use. This mindfulness program aims to reduce stress. Studies have found that participants usually feel less stressed after completing the program, with no significant reports of harmful effects.

For Learning to BREATHE Plus (L2B PLUS), which includes a tech component, research also suggests it is safe and well-received. Participants find it easy to use, and there are no major safety concerns. Both programs focus on mindfulness and stress reduction, offering safe options for managing stress and improving mental health.12345

Why are researchers excited about this trial?

Researchers are excited about Learning to BREATHE (L2B) and Learning to BREATHE Plus (L2B PLUS) because they offer a fresh approach to managing stress through mindfulness techniques. Unlike standard stress treatments, which often involve medication or traditional talk therapy, these methods focus on teaching mindfulness and emotional regulation, empowering individuals to handle stress more effectively on their own. L2B PLUS goes a step further by incorporating additional elements to enhance these mindfulness practices, potentially offering even greater benefits. This approach is particularly appealing as it promotes self-awareness and personal resilience, which can lead to long-lasting stress management without relying solely on medication.

What evidence suggests that this trial's treatments could be effective for reducing depression, anxiety, and stress?

Research has shown that the Learning to BREATHE (L2B) program, which participants in this trial may receive, helps reduce stress and depression in students. Studies have found that participants experience less depression and feel more satisfied with their lives, with one key result being a 10% drop in self-reported stress levels. Meanwhile, Learning to BREATHE Plus (L2B PLUS), another treatment option in this trial, shows early signs of being practical and well-received, with possible benefits like better mindfulness and emotion control. Both programs use mindfulness techniques to help manage stress and improve overall mental health.56789

Who Is on the Research Team?

RL

Rachel Lucas-Thompson, Dr.

Principal Investigator

Colorado State University

Are You a Good Fit for This Trial?

This trial is for U.S. college students who are struggling with depression, anxiety, and stress but aren't getting enough mental health support. Participants should be interested in trying mindfulness-based interventions or health education programs.

Inclusion Criteria

Enrolled in a college or university
Experiencing elevated stress
Plan to be available in-person in the semester following the study
See 2 more

Exclusion Criteria

I have thoughts of harming myself.
I experience multiple symptoms of depression.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants undergo a 6-week intervention with either L2B PLUS, L2B, or HealthEd

6 weeks
Weekly group sessions

Follow-up

Participants are monitored for outcomes such as depression, anxiety, and stress

32 weeks
3 visits; baseline, after 6-week intervention, and at 6-month follow-up

What Are the Treatments Tested in This Trial?

Interventions

  • Learning to BREATHE
  • Learning to BREATHE Plus
Trial Overview The study tests if a multi-modal supplement can enhance the effects of a mindfulness program called 'Learning to BREATHE Plus' compared to just 'Learning to BREATHE' or a standard HealthEd program in reducing mental health issues.
How Is the Trial Designed?
3Treatment groups
Experimental Treatment
Active Control
Group I: Learning to BREATHE Plus (L2B PLUS)Experimental Treatment1 Intervention
Group II: Learning to BREATHE (L2B)Active Control1 Intervention
Group III: HealthEdActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Colorado State University

Lead Sponsor

Trials
138
Recruited
38,200+

University of Colorado, Denver

Collaborator

Trials
1,842
Recruited
3,028,000+

University of Minnesota

Collaborator

Trials
1,459
Recruited
1,623,000+

National Center for Complementary and Integrative Health (NCCIH)

Collaborator

Trials
886
Recruited
677,000+

Macalester College

Collaborator

Citations

1.learning2breathe.orglearning2breathe.org/research-2/
L2B ResearchResults: Participation in the intervention was associated with significant increase in students' life satisfaction, and significant decrease in depression and ...
New study shows efficacy of Learning to BREATHE ...Additionally, there was a 10% decrease in the self-reported amount of stress in the past week. For more information about Learning to BREATHE: A Mindfulness ...
Learning to BREATHE “Plus”: A Multi-Modal Adaptive ...There is growing evidence to support the effectiveness of Learning to BREATHE (L2B) (6), an MBI that is rooted in the philosophy of mindfulness ...
The Effectiveness of the Learning to BREATHE Program on ...These findings provide promising evidence of the effectiveness of Learning to Breathe on the development of key social-emotional learning skills ...
The Effectiveness of Mindfulness-Based Stress Reduction ...MBSR has also shown to be effective in reducing the stress, and increasing perceived quality of life and self-compassion among healthcare profes- sionals ( ...
Learning to BREATHE: A Pilot Study of a Mindfulness-Based ...Researchers hypothesized that a 6-week mindfulness-based intervention would lower participants' perceived stress while increasing their reported levels of self ...
Learning to BREATHE “Plus”: A Multi-Modal Adaptive ...A technological supplement for MBIs, which incorporates multiple technological elements to support (a) skill transfer from the group MBI to daily life.
The influence of mindfulness-based stress reduction on ...The aim of the study was to explore healthcare professionals' experiences of how attending a course in Mindfulness-Based Stress Reduction influenced their work ...
An intervention to foster mindfulness in adolescenceIn the current study, we focused on an MBI with a growing evidence base to support its efficacy: Learning to BREATHE (L2B) (Broderick & Frank, ...
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