Treatment for Memory, Delayed

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of California Los Angeles, Los Angeles, CA
Memory, Delayed
Eligibility
18+
All Sexes
What conditions do you have?
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Study Summary

The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by application of auditory and electrical stimulations during sleep and its effect on modulating memory processes.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Other trials for Memory, Delayed

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 1-2 days contained within the participants' 1-2 week hospital stay; Specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks

Week 2
Neuronal replay index
Power sleep oscillations
Week 2
Recognition Accuracy
Week 2
Recognition Discriminability (D-prime)

Trial Safety

Safety Progress

1 of 3

Other trials for Memory, Delayed

Trial Design

0 Treatment Group

80 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · N/A

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
Closest Location: University of California Los Angeles · Los Angeles, CA
Photo of university of california los angeles 1Photo of university of california los angeles 2Photo of university of california los angeles 3
2006First Recorded Clinical Trial
2 TrialsResearching Memory, Delayed
130 CompletedClinical Trials

Who is running the clinical trial?

University of California, Los AngelesLead Sponsor
1,381 Previous Clinical Trials
6,521,067 Total Patients Enrolled
1 Trials studying Memory, Delayed
70 Patients Enrolled for Memory, Delayed
University of IowaOTHER
400 Previous Clinical Trials
786,735 Total Patients Enrolled
National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,239 Previous Clinical Trials
450,492 Total Patients Enrolled
1 Trials studying Memory, Delayed
70 Patients Enrolled for Memory, Delayed

Eligibility Criteria

Age 18+ · All Participants · 3 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.