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Brain Stimulation for Memory Enhancement During Sleep Cycles

N/A
Recruiting
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
All epilepsy patients between the ages of 18 and 65 who undergo depth electrode placement for clinical purposes
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
Awards & highlights

Study Summary

This trial will study how people's brains process and store memories while they sleep, by recording brain activity at different levels of resolution. They will also study how different types of stimulations during sleep can affect memory processes.

Who is the study for?
This trial is for epilepsy patients aged 18-65 undergoing depth electrode placement. They must be willing to consent and participate, as determined by the epilepsy surgery team after neuropsychological and psychiatric evaluation. Those with additional neurological or psychiatric conditions posing risks are excluded.Check my eligibility
What is being tested?
The study aims to understand memory processes during sleep by recording brain activity in humans through various methods. It will also explore how auditory and electrical stimulations applied during sleep can affect memory consolidation.See study design
What are the potential side effects?
Since this trial involves non-pharmacological interventions like auditory and electrical stimulation, side effects may include discomfort at the electrode sites, potential sleep disturbances, or temporary changes in mood or cognition.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am an epilepsy patient aged 18-65 and will have a depth electrode placement.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1-2 days contained within the participants' 1-2 week hospital stay; specifically for each experiment, the outcome measure will be computed during the pre- and post-sleep memory tasks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Recognition Accuracy
Recognition Discriminability (D-prime)
Secondary outcome measures
Neuronal replay index
Power sleep oscillations

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)NIH
1,337 Previous Clinical Trials
648,764 Total Patients Enrolled
University of California, Los AngelesLead Sponsor
1,525 Previous Clinical Trials
10,275,953 Total Patients Enrolled
University of IowaOTHER
444 Previous Clinical Trials
878,920 Total Patients Enrolled

Media Library

Treatment Clinical Trial Eligibility Overview. Trial Name: NCT05452122 — N/A
Delayed Memory Research Study Groups:
Delayed Memory Clinical Trial 2023: Treatment Highlights & Side Effects. Trial Name: NCT05452122 — N/A
Treatment 2023 Treatment Timeline for Medical Study. Trial Name: NCT05452122 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants being enrolled for the trial presently?

"Indeed, the clinicaltrials.gov website indicates that enrolment is ongoing for this trial which was published on July 13th 2022 and last updated on August 12th 2022. 80 patients are needed to be filled at a single site."

Answered by AI

What is the current participant intake for this experiment?

"Affirmative. Perusing the information hosted on clinicaltrials.gov reveals that this trial is still looking for participants, with 80 people required from 1 site. This research was first posted July 13th 2022 and last edited August 12th 2022."

Answered by AI

Does this research encompass individuals above the age of eighty?

"In accordance with the study's prerequisites, participants must be at least 18 years of age and not exceed 65 to qualify."

Answered by AI

What criteria must be met in order to join this clinical research?

"This trial has a target recruitment of 80 participants aged 18-65 with memory impairment. To be considered eligible, patients must pass neuropsychological testing and present satisfactory psychiatric evaluation results as determined by the epilepsy surgery team. Additionally, they must consent to take part in this study willingly."

Answered by AI
~47 spots leftby Aug 2026