500 Participants Needed

Molecular Analysis for Childhood Melanoma

AP
Overseen ByAlberto Pappo, MD
Age: < 65
Sex: Any
Trial Phase: Academic
Sponsor: St. Jude Children's Research Hospital
Stay on Your Current MedsYou can continue your current medications while participating
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to better understand the molecular makeup of skin lesions in children and teens. By analyzing tissue samples from these lesions, researchers hope to learn more about conditions like melanoma and other related skin issues. This observational study will not involve any new treatments but will collect valuable information. Children and teens under 19 with a confirmed or suspected skin lesion, such as melanoma or lesions with unclear behavior, might be suitable candidates if tissue samples from their lesions are available for study. As an unphased trial, this study offers a unique opportunity to contribute to important research that could improve future diagnosis and treatment of skin conditions in young people.

Do I need to stop my current medications for the trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about this trial because it focuses on understanding the molecular details of melanocytic lesions in children and adolescents. Unlike traditional approaches that directly aim to treat these lesions, this observational study seeks to gather detailed genetic and molecular information, which could lead to more precise and effective treatments in the future. By analyzing these lesions at the molecular level, scientists hope to uncover specific markers or pathways that can be targeted in future therapies, potentially leading to breakthroughs in personalized medicine for melanoma.

Who Is on the Research Team?

AP

Alberto Pappo, MD

Principal Investigator

St. Jude Children's Research Hospital

Are You a Good Fit for This Trial?

Inclusion Criteria

Spitzoid melanoma/atypical Spitz tumor Congenital melanoma
Melanoma arising in a giant congenital nevus
Conventional or "adult-type" melanoma
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Molecular Analysis

Comprehensive molecular analysis of tumor samples from paraffin embedded and/or frozen tissue

At participant enrollment

Follow-up

Participants are monitored for overall survival and other outcomes

Up to 10 years

What Are the Treatments Tested in This Trial?

Interventions

  • Observational Study

Find a Clinic Near You

Who Is Running the Clinical Trial?

St. Jude Children's Research Hospital

Lead Sponsor

Trials
451
Recruited
5,326,000+