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Bone Graft

Xenograft - Autogenous 1:4 for Dental Implants

N/A

Waitlist Available

Led By Lorenzo Mordini, DDS, MS

Research Sponsored by Tufts University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients with full maxillary edentulism or Kennedy class I or III

Patients with two stage sinus augmentations with less than 5mm residual bone height in need of augmentation for implant placement

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 4 months from surgery

Awards & highlights

Study Summary

"This trial aims to assess bone healing four months after a specific type of sinus augmentation procedure using a combination of autologous bone and xenograft, compared to using xenograft alone. The evaluation

Who is the study for?

This trial is for adults aged 18-100 who are patients at Tufts School of Dental Medicine, needing bone grafts for dental implants due to significant tooth loss. They must have a specific amount of residual bone height and not be pregnant, breastfeeding, or heavy smokers. Those with osteoporosis, prior sinus procedures, existing sinus issues, or conditions affecting bone metabolism can't join.Check my eligibility

What is being tested?

The study tests the effectiveness of two types of bone healing after a sinus lift augmentation: one using a mix of the patient's own bone (autograft) with xenograft material versus using only xenograft material. The outcomes will be measured through radiographic analysis and tissue samples at four months post-procedure.See study design

What are the potential side effects?

Potential side effects may include discomfort at the site where autologous bone is taken from, swelling or infection in the sinuses following augmentation, and possible adverse reactions to anesthesia used during these surgical procedures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have no upper teeth or missing teeth except for the front ones.

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I need a sinus lift for dental implants due to having less than 5mm of bone height.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 4 months from surgery

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~4 months from surgery

This trial's timeline: 3 weeks for screening, Varies for treatment, and 4 months from surgery for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Histological analysis

Secondary outcome measures

Radiographic bone height gain at 4 months

Volumetric bone analysis 4 months post sinus augmentation

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Xenograft - Autogenous 1:4Experimental Treatment2 Interventions

Sinus grafted with a ratio of Xenograft - Autogenous 1:4

Group II: Xenograft aloneActive Control2 Interventions

Sinus grafted with Xenograft only

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Tufts UniversityLead Sponsor

266 Previous Clinical Trials

662,113 Total Patients Enrolled

1 Trials studying Dental Implants

30 Patients Enrolled for Dental Implants

Lorenzo Mordini, DDS, MSPrincipal InvestigatorTufts Univeristy

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are participants currently being recruited for this ongoing study?

"Information on clinicaltrials.gov reveals that the current trial is not in active recruitment phase. It was initially listed on March 1, 2024, with the most recent update made on January 30, 2024. While this specific study is not accepting participants presently, there are a total of 47 other trials actively seeking candidates for enrollment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Lorenzo Mordini 2024. "Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06247098.

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