Geriatric Care Optimization for Blood Cancers
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to determine if a personalized geriatric optimization plan can improve life and survival for individuals over 60 with blood cancers or bone marrow issues who qualify for a bone marrow transplant. The plan involves specific changes to daily habits such as diet, sleep, and physical activity, and may include new medications or referrals to other doctors. Participants must attend several study visits, complete monthly questionnaires, and wear a fitness tracker for up to six months. This trial suits those over 60 who can communicate in English, have certain blood-related conditions, and qualify for a bone marrow transplant. As an unphased trial, it offers a unique opportunity to contribute to innovative research that could enhance the quality of life for older adults.
Do I need to stop my current medications for the trial?
The trial information does not specify if you need to stop your current medications. It focuses on creating a personalized plan, which might include changes to your medicines, but this would depend on your specific needs.
What prior data suggests that the geriatric optimization plan is safe for patients over 60 with blood cancers?
Research has shown that personalized care plans for older adults with blood cancers are generally well-tolerated. These plans address the specific needs of older patients and include lifestyle changes such as diet and exercise. Although studies do not specify particular side effects, this approach is considered safe and aims to enhance daily life and quality of life without causing harm. Furthermore, the trial's "Not Applicable" phase indicates that the treatment is expected to be safe, as it does not involve a new drug or invasive procedure.12345
Why are researchers excited about this trial?
The Geriatric Optimization Plan (GO!) is unique because it tailors care specifically for older adults with blood cancers, addressing their complex needs beyond just the cancer itself. Unlike traditional treatment options that primarily focus on chemotherapy or targeted drugs, GO! emphasizes personalized supportive care through regular study visits, monthly questionnaires, and the use of accelerometers to monitor physical activity. Researchers are excited about this approach because it aims to improve overall quality of life and potentially enhance treatment outcomes for geriatric patients by considering their holistic health needs.
What evidence suggests that the Geriatric Optimization Plan is effective for improving survival in patients over 60 with blood cancers?
Research has shown that special care plans for older adults can benefit those with blood cancers. In this trial, participants will receive a personalized Geriatric Optimization Plan (GO!), which includes study visits and assessments tailored to individual needs. One study found that using a geriatric assessment, which evaluates an older person's overall health, improved their care. This method focuses on meeting unique needs, such as adjusting diet, sleep, and activity levels. Another study found that these personalized plans can help prepare older patients for treatments like CAR-T therapy, a type of cancer treatment. These findings suggest that a geriatric care plan can enhance treatment effectiveness and improve the quality of life for older patients.12356
Who Is on the Research Team?
Sarah Wall, MD
Principal Investigator
Ohio State University Comprehensive Cancer Center
Are You a Good Fit for This Trial?
This trial is for people over 60 with blood cancers or bone marrow failure who are eligible for a stem cell transplant. They must be able to understand English and commit to the study's full duration. Those with dementia, no transplant planned within 6 months, or a scheduled transplant within 30 days can't join.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Geriatric Optimization (GO!) Plan
Participants undergo a personalized geriatric optimization plan with study visits and monthly questionnaires
Transplant Preparation
Participants are prepared for allogeneic hematopoietic cell transplant, including hospital admission
Follow-up
Participants are monitored for safety and effectiveness after transplant
What Are the Treatments Tested in This Trial?
Interventions
- Geriatric Optimization Plan
Find a Clinic Near You
Who Is Running the Clinical Trial?
Ohio State University Comprehensive Cancer Center
Lead Sponsor