Lung Cancer Screening Promotion for Lung Cancer

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Abramson Cancer Center at Penn Medicine

Disqualifiers: Not eligible for screening, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how to better communicate lung cancer screening information to people in high-pollution areas, such as parts of Philadelphia. It compares the effects of two videos: one focuses on smoking risks, while the other addresses both smoking and environmental risks. The study seeks English-speaking individuals aged 50 to 80 with a history of heavy smoking who live in specific areas. Participants must have had a recent primary care visit at Penn Medicine. The goal is to find better ways to encourage lung cancer screening and reduce health disparities. As an unphased trial, this study allows participants to contribute to important research that could improve health communication and screening rates.

Do I have to stop taking my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It seems to focus on lung cancer screening and communication, so it's best to ask the trial coordinators for more details.

What prior data suggests that this risk communication approach is safe for promoting lung cancer screening?

Research has shown that using videos to share information about lung cancer screening is generally safe. These videos explain both the benefits and possible risks of screening, helping people understand the importance of getting screened for lung cancer.

The video in this study discusses the risks from smoking and the environment. It resembles other digital tools designed for people with varying education levels. These tools assist individuals in making informed choices about lung cancer screening.

Overall, no evidence suggests that watching these videos is unsafe. The goal is to educate and inform, helping communities understand their risk and the screening process better. ^{1 2 3}

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores innovative ways to promote lung cancer screening through educational videos. Unlike traditional methods that mainly focus on the dangers of smoking, one of the videos in this trial includes information about both smoking and environmental risks, offering a more comprehensive understanding of factors contributing to lung cancer. The goal is to see if this broader approach encourages more people to get screened, potentially leading to earlier detection and better outcomes. This trial could pave the way for more effective public health campaigns that address multiple risk factors, not just smoking.

What evidence suggests that this trial's videos could be effective for promoting lung cancer screening?

Research shows that technology, such as the video in this study, can encourage lung cancer screening. Studies have found that these tools, especially when combined with guidance from a patient navigator, increase screening rates among high-risk individuals. In this trial, participants in the Intervention Arm will watch a video covering both environmental and smoking risks. Research has shown that discussing multiple risks together can enhance understanding and motivate action. By detailing both smoking and environmental risks, the video aims to encourage more people, particularly in areas with higher environmental challenges, to consider lung cancer screening. Meanwhile, participants in the Control Video Arm will watch a video that provides information only about smoking risks. ^{4 5 6 7 8}

Who Is on the Research Team?

Katharine Rendle, PhD,MSW,MPH

Principal Investigator

University of Pennsylvania

Andy Tan, PhD,MPH,MBA

Principal Investigator

University of Pennsylvania

Are You a Good Fit for This Trial?

This trial is for individuals aged 50-80 who have a significant history of smoking and have visited Penn Medicine in the last two years. They must live in specific zip codes, speak English, and be able to view videos and take surveys online. Those with previous lung cancer screenings or diagnoses are excluded.

Inclusion Criteria

Patient interview participants: Ages 50 - 80 years

Participants must be between 50 and 80 years old.

Patient interview participants: Able to participate in a video-conference interview using a HIPAA-compliant platform or able to participate in an interview over the phone

Exclusion Criteria

Pilot trial participants: Do not meet inclusion criteria

You have already taken part in interviews with patients as part of a trial.

Patient interview participants: Not eligible for lung cancer screening

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants view a health education video about smoking and environmental risks

1 day

1 visit (in-person or virtual)

Follow-up

Participants are monitored for lung cancer screening completion and intentions

6 months

What Are the Treatments Tested in This Trial?

Interventions

• Control video
• Intervention video

Trial Overview Project PLUS tests an enhanced risk communication approach to encourage lung cancer screening intentions among people from areas with high environmental pollution. It involves comparing reactions to an intervention video versus a control video after conducting qualitative interviews.

How Is the Trial Designed?

Group I: Intervention Arm Experimental Treatment 1 Intervention

This arm includes patients who view the integrated health video that provides information about both smoking and environmental risk.

Group II: Control Video Arm Experimental Treatment 1 Intervention

This arm includes patients who view the integrated health video that provides information ONLY about smoking risk.

Who Is Running the Clinical Trial?

Abramson Cancer Center at Penn Medicine

Lead Sponsor

Trials

425

Recruited

464,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12386249/

Effectiveness of Technology-Based Interventions in Promoting ... This study reviews how technology-based interventions have been designed and implemented to promote lung cancer screening (LCS), ...

2. mdpi.com mdpi.com/1660-4601/22/8/1250

Effectiveness of Technology-Based Interventions in ... This study reviews how technology-based interventions have been designed and implemented to promote lung cancer screening (LCS), support shared ...

3. sciencedirect.com sciencedirect.com/science/article/pii/S2347562525000940

Interventions targeted to improve lung cancer screening ... Combined intervention and patient navigation are most effective in increasing lung cancer screening uptake among high-risk individuals.

4. researchgate.net researchgate.net/publication/394649547_Effectiveness_of_Technology-Based_Interventions_in_Promoting_Lung_Cancer_Screening_Uptake_and_Decision-Making_Among_Patients

(PDF) Effectiveness of Technology-Based Interventions in ... This study reviews how technology-based interventions have been designed and implemented to promote lung cancer screening (LCS), support shared ...

5. jtocrr.org jtocrr.org/article/S2666-3643(23)00008-5/fulltext

Interventions Designed to Increase the Uptake of Lung ... Participation in lung cancer screening (LCS) is lower in populations with the highest burden of lung cancer risk (through the social ...

6. sciencedirect.com sciencedirect.com/science/article/pii/S2772628225000172

Developing a digital video to support lung cancer ... We developed a digital tool specifically to support lung cancer screening in diverse populations, including those with varied educational attainment.

7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC6543473/

Impact of a Lung Cancer Screening Information Film ... Rationale: Lung cancer screening has the potential to save lives, but it also carries a risk of potential harms. Explaining the benefits and harms of ...

8. go2.org go2.org/risk-early-detection/about-screening/

About Screening - GO2 for Lung Cancer Watch our Screening Saves Lives! video to find out more about the importance of low-dose CT (LDCT) lung cancer screening. If you're a healthcare ...