Light Exposure + Meal Timing for Circadian Rhythm Management
(LipidPRC Trial)
Trial Summary
What is the purpose of this trial?
The aim of this study is to determine the principal time cue (light or meals) for resetting circadian rhythms in melatonin and metabolic outcomes.
Do I have to stop taking my current medications for the trial?
Yes, you will need to refrain from taking medications and supplements during the study, except for birth control.
What data supports the effectiveness of the treatment Light Exposure + Meal Timing for Circadian Rhythm Management?
Research suggests that time-restricted eating (TRE), which involves eating within a specific time window, can help with weight loss, improve glucose tolerance, and enhance overall metabolic health. Additionally, meal timing and light exposure can synchronize biological clocks, potentially improving sleep patterns and metabolic functions.12345
Is time-restricted eating safe for humans?
How does the treatment of light exposure and meal timing for circadian rhythm management differ from other treatments?
This treatment is unique because it combines light exposure and meal timing to align the body's internal clock with natural day-night cycles, potentially improving metabolic health and reducing the risk of chronic diseases. Unlike traditional treatments that may focus on medication or diet changes alone, this approach uses the timing of meals and light as natural cues to synchronize the body's circadian rhythms.345910
Eligibility Criteria
This trial is for healthy individuals aged 18-30 who don't smoke, use drugs, or have sleep disorders. They must maintain an 8-hour sleep schedule and avoid caffeine, alcohol, and most medications during the study. Participants should have a BMI between >18 and <30 kg/m2.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo interventions involving 6.5-hour bright light exposure and time-restricted eating to study circadian rhythm shifts
Follow-up
Participants are monitored for changes in melatonin and lipid levels after interventions
Treatment Details
Interventions
- 12-h meal window
- Bright Light
- Dim light
- Time-restricted eating
Find a Clinic Near You
Who Is Running the Clinical Trial?
Brigham and Women's Hospital
Lead Sponsor