2400 Participants Needed

Inflammatory Bowel Disease for Children

(CIDsCaNN Trial)

Recruiting at 12 trial locations
AM
Overseen ByAnne M Griffiths, MD, FRCPC
Age: < 18
Sex: Any
Trial Phase: Academic
Sponsor: The Hospital for Sick Children
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to understand why inflammatory bowel disease (IBD) is common in Canadian children and teenagers. Researchers seek to identify the best treatments for different types of IBD by examining various factors, such as environment and genetics, near the onset of the disease. They will measure outcomes like symptom relief, growth, and intestinal healing. Children and teens diagnosed with Crohn's disease, ulcerative colitis, or undefined IBD may be suitable for this study. As an unphased study, this trial offers participants the chance to contribute to groundbreaking research that could enhance the understanding and treatment of IBD in young people.

Why are researchers excited about this trial?

Researchers are excited about this trial because it aims to better understand and improve the care for children with inflammatory bowel disease (IBD) in Canada. Unlike standard treatments such as aminosalicylates, corticosteroids, and immunosuppressants, which primarily focus on managing symptoms, this trial seeks to identify more precise and personalized treatment approaches. By analyzing data and outcomes from various centers, the trial could reveal new insights into how different treatments affect children differently, paving the way for more effective and tailored therapies.

Who Is on the Research Team?

AM

Anne M Griffiths, MD, FRCPC

Principal Investigator

The Hospital for Sick Children

Are You a Good Fit for This Trial?

Inclusion Criteria

diagnosed with IBD - Crohn's, ulcerative colitis or inflammatory bowel disease undefined

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive treatment and are monitored for initial treatment response using PCDAI, PUCAI, and other clinical assessments

18 months
Visits at 6, 12, and 18 months

Follow-up

Participants are monitored for sustained clinical remission and intestinal healing

Until transfer to adult care

What Are the Treatments Tested in This Trial?

Find a Clinic Near You

Who Is Running the Clinical Trial?

The Hospital for Sick Children

Lead Sponsor

Trials
724
Recruited
6,969,000+

Stollery Children's Hospital

Collaborator

Trials
25
Recruited
25,900+

IWK Health Centre

Collaborator

Trials
131
Recruited
112,000+

Montreal Children's Hospital of the MUHC

Collaborator

Trials
32
Recruited
117,000+

St. Justine's Hospital

Collaborator

Trials
205
Recruited
87,300+

Health Sciences Centre, Winnipeg, Manitoba

Collaborator

Trials
18
Recruited
11,600+

Children's Hospital of Eastern Ontario

Collaborator

Trials
134
Recruited
61,000+

Eastern Health

Collaborator

Trials
22
Recruited
29,800+

Children's Hospital of Western Ontario

Collaborator

Trials
6
Recruited
5,900+

British Columbia Children's Hospital

Collaborator

Trials
27
Recruited
15,600+
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