Surgical Site Infections for Abdominal Surgery
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial examines why some patients develop infections after open abdominal surgery. Researchers aim to determine if certain bacteria on the skin or in the gut during surgery cause these infections. They will compare patients who develop infections with those who do not, focusing on the types of bacteria present. This study targets adults undergoing open abdominal surgery with a large incision. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group, offering participants a chance to contribute to significant medical advancements.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover how surgical site infections (SSIs) develop by studying the microbiome of patients undergoing open gastrointestinal (GI) surgery. Unlike traditional treatments that focus on treating infections after they occur, this research could lead to preventative strategies by understanding the role of bacteria in wound healing and infection. By matching patients with and without SSIs in terms of age, sex, diagnosis, and wound class, researchers hope to pinpoint specific microbial factors that contribute to or protect against these infections. This could pave the way for innovative approaches to prevent SSIs, potentially reducing the reliance on antibiotics and improving patient outcomes.
Who Is on the Research Team?
Jennifer Rickard
Principal Investigator
University of Minnesota
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Surgery and Sample Collection
Patients undergo open GI surgery, and samples are collected from the incision site and GI tract
Postoperative Monitoring
Patients are monitored for signs of surgical site infections (SSI) up to 30 days postoperatively
Follow-up
Participants are monitored for safety and effectiveness after the initial postoperative period
What Are the Treatments Tested in This Trial?
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Patients with SSI
age-, sex-, diagnosis-, and wound class-matched control patients without SSI
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Minnesota
Lead Sponsor
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