Mindfulness Meditation for Pulmonary Hypertension

(MMPH Trial)

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Overseen ByTania Von Visger, PhD, RN
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: State University of New York at Buffalo
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a mindfulness meditation program to help manage pulmonary hypertension, a type of high blood pressure affecting the lungs, in underserved racial minority adults. Participants will engage in online and app-based meditation sessions designed to reduce stress and improve resilience. The trial aims to determine if this program can enhance overall health management for individuals with this condition. Those diagnosed with pulmonary hypertension, who self-identify as racial minorities, and can participate in mindfulness activities for eight weeks might be a good fit. As an unphased trial, this study offers a unique opportunity to explore innovative health strategies and contribute to research that could benefit others with similar conditions.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on mindfulness practices, so it's likely you can continue your medications, but please confirm with the trial organizers.

What prior data suggests that this mindfulness meditation program is safe for pulmonary hypertension patients?

Research has shown that mindfulness programs, such as Mindfulness Meditation for Pulmonary Hypertension (MMPH), are generally safe. Studies on similar programs have found no major safety issues for participants. People typically handle these programs well, with no reports of serious problems. This suggests that MMPH is likely safe for those with pulmonary hypertension.12345

Why are researchers excited about this trial?

Researchers are excited about the Mindfulness Meditation for Pulmonary Hypertension (MMPH) program because it offers a non-pharmaceutical approach to managing the condition, which traditionally relies on medications like endothelin receptor antagonists, phosphodiesterase-5 inhibitors, and prostacyclin analogs. This mindfulness meditation program is distinctive because it aims to reduce stress and improve heart health through mental and emotional regulation, potentially offering benefits without the side effects associated with medication. By focusing on improving mental well-being, MMPH could enhance overall quality of life for patients with pulmonary hypertension, especially in underserved racial minority adults who may have less access to traditional treatments.

What evidence suggests that Mindfulness Meditation for Pulmonary Hypertension (MMPH) could be effective for managing pulmonary hypertension?

Research suggests that mindfulness meditation might help manage symptoms of pulmonary hypertension, which is high blood pressure in the lungs. Some studies have examined similar mindfulness programs, but results have been mixed. For example, one study found that a web-based mindfulness meditation program did not significantly improve symptoms or quality of life for people with pulmonary hypertension. However, mindfulness practices are generally believed to reduce stress and improve overall well-being, which could benefit those with pulmonary hypertension. In this trial, participants in the Treatment Arm will first receive the Mindfulness Meditation for Pulmonary Hypertension (MMPH) intervention, while those in the Comparison Arm will receive it after the Treatment Arm completes the intervention. Although strong evidence is limited, the idea is that mindfulness can boost mental strength and help manage stress.12678

Who Is on the Research Team?

TV

Tania Von Visger

Principal Investigator

State University of New York at Buffalo School of Nursing

Are You a Good Fit for This Trial?

Inclusion Criteria

PH confirmed by standard guidelines
Able to ambulate independently
English-speaking
See 3 more

Exclusion Criteria

Known pregnancy
Have psychiatric conditions requiring hospitalization within the last year
You currently practice mind-body techniques.
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks
1 visit (virtual)

Treatment

Participants engage in an 8-week Mindfulness Meditation Program with two Zoom sessions and daily mobile app practice

8 weeks
2 visits (virtual)

Follow-up

Participants are monitored for changes in depressive symptoms, quality of life, and mindfulness levels

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Mindfulness Meditation for Pulmonary Hypertension (MMPH)
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Active Control
Group I: Treatment ArmExperimental Treatment1 Intervention
Group II: Comparison Arm or Waited List ArmActive Control1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

State University of New York at Buffalo

Lead Sponsor

Trials
279
Recruited
52,600+

National Center for Advancing Translational Sciences (NCATS)

Collaborator

Trials
394
Recruited
404,000+

Published Research Related to This Trial

In a study of 108 patients with pulmonary arterial hypertension (PAH), the use of actigraphy to measure daily life physical activity (DLPA) showed that selexipag did not lead to significant improvements in physical activity levels compared to placebo over 24 weeks.
Despite high compliance with the accelerometer, changes in daily physical activity were small and variable, indicating that selexipag may not have a meaningful impact on improving quality of life through increased physical activity in this patient population.
Assessing Daily Life Physical Activity by Actigraphy in Pulmonary Arterial Hypertension: Insights From the Randomized Controlled Study With Selexipag (TRACE).Howard, LS., Rosenkranz, S., Frantz, RP., et al.[2023]

Citations

Piloting Mindfulness Meditation Program for Underserved ...Mindfulness Meditation for Pulmonary Hypertension (MMPH): Eight weeks of Mindfulness Meditation practice for patients with Pulmonary Hypertension condition.
Effects of a Web-based Multiple Component Mindfulness ...The purpose of this pilot study was to evaluate the preliminary efficacy of a virtual Mindfulness Meditation Intervention for patients with Pulmonary ...
A pilot randomised controlled trial investigating a mindfulness ...We wished to determine whether a trial of MBSR for people with PAH would be feasible.
Effects of A Web-based Multiple Component Mindfulness ...Effects of A Web-based Multiple Component Mindfulness Meditation for Pulmonary Hypertension (MMPH) ... data show no significant difference ...
Web-based mindfulness meditation for pulmonary ...In this pilot randomized controlled trial in participants with pulmonary hypertension, web-based mindfulness meditation did not improve ...
Piloting Mindfulness Meditation Program for Underserved ...The research on mindfulness-based stress reduction (MBSR), which is similar to MMPH, does not report any safety concerns for humans, suggesting it is generally ...
Mindfulness-Based Interventions for Chronic Pulmonary ...The analysis focuses on the effects of these interventions and their role in improving psychological distress, reducing anxiety, depression, low ...
Web-based mindfulness meditation for pulmonary ...In this pilot randomized controlled trial in participants with pulmonary hypertension, web-based mindfulness meditation did not improve physical ...
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