300 Participants Needed

AI-Based Detection for Uterine Cancer

Recruiting at 2 trial locations
CT
Overseen ByClinical Trials Referral Office
Age: 18+
Sex: Female
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores whether artificial intelligence (AI) can detect endometrial cancer and its early warning signs by analyzing images from a transvaginal ultrasound. The goal is to determine if AI can make early detection easier and more reliable for women experiencing post-menopausal bleeding. Participants will undergo a transvaginal ultrasound and have their medical records reviewed. Women who have experienced post-menopausal bleeding and have had an endometrial biopsy might be suitable for this study.

As a Phase 2 trial, this research focuses on measuring the effectiveness of the AI technology in an initial, smaller group of people, offering participants a chance to contribute to potentially groundbreaking advancements in early cancer detection.

Why are researchers excited about this trial?

Researchers are excited about this trial because it explores a new way to detect endometrial cancer and atypical hyperplasia using an AI-based classifier with transvaginal ultrasound. Unlike traditional methods that may rely heavily on invasive biopsies or more subjective interpretations of ultrasound results, this approach aims to enhance accuracy by applying advanced AI technology to ultrasound imaging. This could lead to earlier and more precise diagnoses, especially in patients with post-menopausal bleeding, which is crucial for effective treatment and management.

Who Is on the Research Team?

GE

Gretchen E Glaser, MD

Principal Investigator

Mayo Clinic in Rochester

Are You a Good Fit for This Trial?

Inclusion Criteria

I have had at least one episode of postmenopausal bleeding.
I am 55 years old or older.
I will have my endometrial biopsy done at Mayo Clinic.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Observational

Patients undergo a transvaginal ultrasound examination and endometrial sampling per standard of care and have their medical records reviewed

Baseline

Follow-up

Participants are monitored for safety and effectiveness after the observational study

4 weeks

What Are the Treatments Tested in This Trial?

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: ObservationalExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+