700 Participants Needed

LASIK, SMILE, and PRK for Vision Correction

LS
Overseen ByLinda Schwartz
Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: Stanford University
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial examines how three types of eye surgeries—LASIK, SMILE, and PRK—affect vision and quality of life for physicians. The goal is to determine how these treatments might reduce the need for glasses. It suits physicians or medical students who haven't undergone eye surgery and seek more freedom from glasses. Participants must speak English, be 21 or older, and attend follow-up appointments for a year. As an unphased trial, this study allows participants to contribute to valuable research that could improve vision correction options for medical professionals.

Do I need to stop my current medications for this trial?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial team or your doctor.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that LASIK, PRK, and SMILE surgeries are generally safe, though each has potential side effects.

For LASIK, studies indicate that 99.5% of patients achieve 20/40 vision or better. However, some may temporarily experience dry eyes, glare, halos, or trouble seeing at night after the procedure.

PRK is also considered safe, with complications being rare and usually minor. Patients might feel as if something is in their eye or experience blurry vision and tearing, which typically resolve quickly. Long-term risks include changes in vision and dry eyes.

SMILE surgery is known for its high safety and stable results. However, some may see glare or halos around lights at night. Large studies report low rates of serious complications.

In summary, while these eye surgeries are generally well-tolerated, they can have temporary side effects. Most patients recover well and achieve improved vision.12345

Why are researchers excited about this trial?

Researchers are excited about LASIK, SMILE, and PRK surgeries because they offer distinct approaches to correcting vision in physicians. LASIK is unique with its use of a laser to create a flap in the cornea, allowing for a quick recovery time and minimal discomfort. SMILE stands out by using a minimally invasive technique that doesn't require a flap, potentially reducing the risk of dry eye. PRK, on the other hand, removes the cornea's outer layer entirely and allows for a more gradual healing process, which can be beneficial for patients with thinner corneas. Each of these methods provides unique advantages, making them promising options for those in the medical field seeking vision correction.

What evidence suggests that this trial's treatments could be effective?

Research has shown that LASIK surgery is highly effective, with 99% of patients achieving 20/20 vision or better. Most patients express satisfaction, with 98% happy with their results. In PRK surgery, over 90% of patients also achieve 20/20 vision or better, and 95% are pleased with the outcome. For SMILE surgery, studies indicate that 90% of eyes reach 20/20 vision three years after the procedure. This trial will compare LASIK, PRK, and SMILE, all of which have demonstrated excellent results in improving vision and patient satisfaction in previous studies.16789

Who Is on the Research Team?

EE

Edward E. Manche, MD

Principal Investigator

Stanford University

Are You a Good Fit for This Trial?

Inclusion Criteria

21 years or older.
A physician or medical student.
Have the ability to give informed consent.
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks
1 visit (in-person)

Pre-operative

Comprehensive eye examination and administration of Quality of Vision Questionnaire

1 week
1 visit (in-person)

Surgery

Participants undergo LASIK, SMILE, or PRK surgery

1 day
1 visit (in-person)

Post-operative

Participants receive topical antibiotics and pred forte drops; follow-up visits at day one, one month, three months, and twelve months

12 months
5 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

12 months
2 visits (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • LASIK
  • PRK
  • SMILE

Find a Clinic Near You

Who Is Running the Clinical Trial?

Stanford University

Lead Sponsor

Trials
2,527
Recruited
17,430,000+

Citations

Functional Outcome and Patient Satisfaction after Laser In Situ ...

Based on this review, worldwide, an average 95.4% of patients were satisfied with their outcome after LASIK surgery. With 16.3 million procedures performed ...

Important LASIK Eye Surgery Statistics to Evaluate Risk

90% of patients achieve at least 20/20 vision through successful LASIK surgery and as many as 50% achieve even better vision than this.

What Five Years of LASIK Eye Surgery Data Reveals

A review of over 82,000 eyes found an average satisfaction rate of 92.6%, with 97.5% of patients recommending LASIK to a friend. Older adults, ...

Facts About LASIK Complications

According to the 2016 Modern LASIK Outcomes study, 99.5% of eyes saw 20/40 or better after LASIK.

LASIK Success Rate & Laser Eye Surgery Statistics

LASIK has a 99% success rate at NVISION, with most patients achieving 20/20 vision or better. Over 98% of patients report high satisfaction, ...

LASIK eye surgery

Risks · Dry eyes. LASIK surgery causes a temporary decrease in tear production. · Glare, halos and double vision. You may have a hard time seeing ...

LASIK Complications and LASIK Eye Surgery Risks

The most common LASIK side effects patients experience include dry eye, glare, halos, or night vision symptoms during the healing process.

Pros and Cons of LASIK: Are the Risks Worth the Cost?

Con: Some LASIK risks are possible · Pro: You can live life without glasses or contacts · Con: The flaps can be injured · Pro: Your vision will be ...

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pubmed.ncbi.nlm.nih.gov

pubmed.ncbi.nlm.nih.gov/40197080

Laser in Situ Keratomileusis Outcomes and Complications

LASIK remains a safe, effective, and highly satisfying refractive surgery, with TG-LASIK demonstrating superior outcomes compared to other LASIK treatments.