Relationship-Centered HIV Prevention for African Immigrants
(MiST-Pathways Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
The goal of this mixed-methods pilot study is to learn whether migration experiences, social bonds, and transnational ties shape HIV prevention decision-making, including HIV testing, HIV self-testing (HIVST), and pre-exposure prophylaxis (PrEP) uptake, among first-generation African immigrants aged 18 to 50 residing in New York and Massachusetts. The main questions it aims to answer are:
* What relationship typologies and migration-related relational mechanisms influence HIV testing, HIVST, and PrEP decision-making among African immigrants?
* Can a relationship-tailored HIV prevention intervention component, co-developed with the community, demonstrate feasibility and acceptability among African immigrants?
* Does exposure to the prioritized intervention component show directional increases in HIV testing intention, willingness to use HIVST, interest in PrEP, and readiness for relationship-based prevention communication? There is no comparison group. All Aim 3 participants receive the same co-developed intervention component.
Participants will:
* Complete a qualitative interview (60-90 minutes) and/or a structured electronic survey (15-20 minutes) about their relationship experiences, migration history, and HIV prevention behaviors.
* Take part in a 3-4 hour structured group deliberation session called a Palava Hut Conversation to co-develop and prioritize HIV prevention intervention ideas.
* Complete a baseline survey, receive the prioritized intervention component in a structured Zoom session, and complete a follow-up survey with an optional 60-90 minute cognitive interview for a subset of participants.
Who Is on the Research Team?
Gloria A. Aidoo-Frimpong, PhD, MPH, MA
Principal Investigator
State University of New York at Buffalo
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Qualitative Interview and Survey
Participants complete a qualitative interview and/or a structured electronic survey about their relationship experiences, migration history, and HIV prevention behaviors.
Palava Hut Conversation
Participants take part in a structured group deliberation session to co-develop and prioritize HIV prevention intervention ideas.
Intervention Delivery
Participants receive the prioritized intervention component in a structured Zoom session.
Follow-up
Participants complete a follow-up survey and an optional cognitive interview to assess feasibility, acceptability, and perceived fit.
What Are the Treatments Tested in This Trial?
Interventions
- Relationship-Centered HIV Prevention Intervention Component
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
Participants matching the relationship typology prioritized through community deliberation in Aim 2 are assigned to receive a single co-developed behavioral intervention component. The intervention is delivered via Zoom in a standardized facilitation structure and focuses on relationship-based HIV prevention communication and decision-making within migration-shaped relationship contexts. Participants complete a baseline survey (T0) before the intervention and a post-intervention survey (T1) immediately after. A subset of participants completes an optional cognitive interview to assess feasibility, acceptability, perceived fit, and evidence of mechanism activation.
Find a Clinic Near You
Who Is Running the Clinical Trial?
State University of New York at Buffalo
Lead Sponsor
Yale University Center for Interdisciplinary Research on AIDS
Collaborator
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