Remote Ischemic Conditioning for Healthy Adults
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial explores how remote ischemic conditioning (RIC) can improve muscle strength and balance in healthy adults. RIC uses a blood pressure cuff on the leg to briefly stop and restart blood flow, potentially protecting organs and enhancing nerve functions. The study will also examine whether combining RIC with balance training provides additional benefits. Healthy adults without vision, balance, or serious heart and lung issues may be suitable for this trial. As an unphased trial, this study offers a unique opportunity to contribute to groundbreaking research that could enhance overall health and well-being.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What prior data suggests that remote ischemic conditioning is safe for healthy adults?
Research has shown that remote ischemic conditioning (RIC) is generally safe. Studies found that stroke patients tolerated RIC well. In these studies, RIC did not cause any serious side effects. Some minor issues, such as skin bruising or swelling, were reported, but these were not serious. Overall, RIC is considered a safe method to aid recovery and improve blood flow in the brain.12345
Why are researchers excited about this trial?
Researchers are excited about remote ischemic conditioning (RIC) because it offers a unique, non-invasive approach to potentially enhance blood flow and protect tissues without the need for pharmaceutical intervention. Unlike standard treatments that might rely on medications to improve circulation or prevent tissue damage, RIC uses a simple blood pressure cuff to intermittently restrict and restore blood flow, which may trigger the body’s natural protective mechanisms. This method could lead to safer, more accessible treatment options, especially for those who may not tolerate medication well. Moreover, exploring the efficacy and mechanisms of RIC could open up new pathways for treating various conditions related to blood flow and tissue health.
What evidence suggests that remote ischemic conditioning is effective for improving muscle strength and balance in healthy adults?
Research shows that remote ischemic conditioning (RIC), which participants in this trial may receive, can greatly aid recovery in various health conditions. Studies have found that RIC improves brain function and reduces damage in people who have had a stroke. For example, RIC has been linked to better recovery outcomes 90 days after a stroke. It works by temporarily reducing blood flow in a controlled way, which seems to protect organs and aid healing. In healthy adults, combining RIC with exercise may increase muscle strength and balance. These findings suggest that RIC could effectively improve both physical and brain health.46789
Who Is on the Research Team?
Swati M Surkar, PT, PhD
Principal Investigator
East Carolina University
Are You a Good Fit for This Trial?
This trial is for healthy young adults who may have a condition called Ocular Ischemia Syndrome. Participants should be interested in exploring how certain non-invasive treatments can potentially improve muscle strength and balance.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Baseline Assessment
Participants undergo H-reflex testing and balance assessments
Treatment
Participants undergo RIC or sham conditioning combined with balance training over multiple sessions
Follow-up
Participants are monitored for changes in H-reflex amplitude and balance performance
What Are the Treatments Tested in This Trial?
Interventions
- Balance training
- Remote Ischemic Conditioning
- Sham Conditioning
Find a Clinic Near You
Who Is Running the Clinical Trial?
East Carolina University
Lead Sponsor