DFG Laser vs CO2 Laser for Pain and Wound Healing
Trial Summary
Will I have to stop taking my current medications?
The trial protocol does not specify if you need to stop taking your current medications. However, if you are using certain topical or systemic retinoids, corticosteroids, or other prescription topical medications on the area of interest, you may need to stop as these are part of the exclusion criteria.
What data supports the effectiveness of the DFG Laser vs CO2 Laser treatment for pain and wound healing?
How does the DFG Laser treatment differ from other treatments for pain and wound healing?
The DFG Laser treatment, which includes fractional CO2 lasers, is unique because it combines fractional photothermolysis (a method that targets small areas of skin) with an ablative wavelength, allowing for effective treatment of scars and skin damage with shorter recovery times and fewer side effects compared to traditional CO2 laser treatments.12356
What is the purpose of this trial?
This research study aims assess whether the Difference Frequency Generation (DFG) laser could be a better alternative to the CO2 laser in terms of reduced side effects and patient downtime.
Research Team
Dieter Manstein, MD, PhD
Principal Investigator
Massachusetts General Hospital
Eligibility Criteria
This trial is for healthy individuals who are interested in participating in a study comparing two types of laser treatments. Specific eligibility criteria have not been provided, so it's best to contact the research team for details.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive treatment with DFG and CO2 lasers on the upper thighs. Pain scores and OCT imaging are recorded.
Follow-up
Participants are monitored for wound healing and dermal vasculature changes using OCT imaging
Treatment Details
Interventions
- CO2 Laser
- DFG Laser
CO2 Laser is already approved in United States, European Union for the following indications:
- Scleroderma-induced microstomia
- Various skin conditions
- Scleroderma-induced microstomia
- Various skin conditions
Find a Clinic Near You
Who Is Running the Clinical Trial?
Massachusetts General Hospital
Lead Sponsor