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Heat Therapy for Alzheimer's Prevention (FIGHT-AD Trial)
N/A
Waitlist Available
Led By Jill Morris
Research Sponsored by University of Kansas Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Post-menopausal
History of or current metabolic impairment (i.e. metabolic syndrome, pre-diabetes, Type 2 Diabetes, etc)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 10 weeks
Awards & highlights
FIGHT-AD Trial Summary
This trial will investigate if heat therapy can improve glucose metabolism in older adults at risk for Alzheimer's and explore its potential effects on brain health.
Who is the study for?
This trial is for people aged 65 or older who are cognitively healthy but at risk for Alzheimer's Disease. They should have stable medication doses, be post-menopausal, and may have a history of metabolic issues like pre-diabetes. Those with Type 1 Diabetes, high cardiovascular risk without clearance, certain chronic diseases, heat intolerance conditions or recent heart problems cannot join.Check my eligibility
What is being tested?
The study tests if water immersion heat therapy can improve blood and brain glucose metabolism in older adults to prevent Alzheimer's Disease. It will also explore how these changes might benefit overall brain health and body metabolism.See study design
What are the potential side effects?
Potential side effects aren't specified but could include discomfort from the heat, dehydration risks or circulatory responses due to temperature changes during the water immersion therapy.
FIGHT-AD Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have gone through menopause.
Select...
I have a history of or currently have a metabolic condition like pre-diabetes or Type 2 Diabetes.
Select...
I am 65 years old or older.
FIGHT-AD Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 10 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~10 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
HbA1C
Insulin sensitivity index
Secondary outcome measures
Fluorodeoxyglucose (FDG) positron emission tomography (PET) Metabolism (Standard Uptake Value Ratio)
FIGHT-AD Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Heat therapy GroupExperimental Treatment1 Intervention
40.5°C water
Group II: Thermoneutral Control GroupPlacebo Group1 Intervention
36°C water
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Who is running the clinical trial?
University of Kansas Medical CenterLead Sponsor
461 Previous Clinical Trials
169,097 Total Patients Enrolled
National Institute on Aging (NIA)NIH
1,669 Previous Clinical Trials
28,005,054 Total Patients Enrolled
Jill MorrisPrincipal InvestigatorUniversity of Kansas Medical Center
1 Previous Clinical Trials
24 Total Patients Enrolled
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there still openings for prospective participants in this study?
"As outlined on clinicaltrials.gov, this trial is not presently recruiting participants; the initial posting was made January 1st 2024 and the last update on August 28th 2023. Even though candidates cannot be recruited for this medical study right now, an incredible 723 other trials are actively accepting subjects at present."
Answered by AI
Who else is applying?
What site did they apply to?
Univeristy of Kansas Medical Center
What portion of applicants met pre-screening criteria?
Met criteria
Did not meet criteria
Why did patients apply to this trial?
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