80 Participants Needed

Bifidobacterium adolescentis for Healthy Aging

(VITAL Trial)

SJ
HY
Overseen ByHariom Yadav, PhD

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional health outcomes in midlife adults. The study explores whether modulation of aging-related biological pathways through the gut microbiome may influence health-related outcomes.

Are You a Good Fit for This Trial?

This trial is for midlife adults who are interested in healthy aging. Participants should be generally healthy without any major medical conditions that could interfere with the study.

Inclusion Criteria

BMI: 20-34.9 kg/m²
I am between 40 and 75 years old.
I am willing and able to agree to participate in the study.

Exclusion Criteria

Intention to have children during study period
Abuse of drugs, alcohol, tobacco, nicotine and other substances
I have a history of chronic liver, kidney, or heart disease.
See 12 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive Bifidobacterium adolescentis (iVS-1) or placebo once daily for 150 days

21 weeks
3 visits (in-person) at baseline, mid-intervention, and end of study

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Bifidobacterium adolescentis (iVS-1)

Trial Overview

The trial is testing if a probiotic called Bifidobacterium adolescentis iVS-1 can improve markers of biological aging, metabolic health, and functional outcomes compared to a placebo. It's randomized and double-blind, meaning neither participants nor researchers know who gets the real probiotic or placebo.

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Bifidobacterium adolescentis iVS-1Experimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Synbiotic Health

Lead Sponsor

MusB Research

Collaborator