2000 Participants Needed

Registry for Pompe Disease

Recruiting at 981 trial locations
PR
TT
Overseen ByTrial Transparency email recommended (Toll free number for US & Canada)
Age: Any Age
Sex: Any
Trial Phase: Academic
Sponsor: Genzyme, a Sanofi Company
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to understand more about Pompe disease, a rare genetic disorder affecting muscle function. By collecting information from individuals with Pompe disease, both those receiving treatment and those who are not, researchers hope to learn about disease progression and the long-term effects of treatments like alglucosidase alfa. This information will help improve patient care and develop better treatment guidelines. Anyone with a confirmed diagnosis of Pompe disease, verified through specific tests, can join this trial. As a Phase 4 trial, this research focuses on understanding how the already FDA-approved treatment benefits more patients, offering valuable insights for participants.

Do I need to stop my current medications to join the trial?

The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.

Why are researchers excited about this trial?

Researchers are excited about the Pompe Disease Registry Protocol because it aims to collect comprehensive data on patients with Pompe disease, which can lead to a deeper understanding of the condition. Unlike treatments that focus solely on managing symptoms, this registry offers a broader perspective by tracking the natural progression of the disease in a real-world setting. The information gathered can help identify patterns, improve current treatments, and possibly lead to the development of new therapies that are more effective and tailored to patient needs.

Who Is on the Research Team?

SD

Study Director

Principal Investigator

Genzyme, a Sanofi Company

Are You a Good Fit for This Trial?

Inclusion Criteria

All patients with a confirmed diagnosis of Pompe disease who have signed the informed consent and authorization form(s) are eligible for inclusion. Confirmed diagnosis is defined as documented GAA enzyme deficiency from blood, skin, or muscle tissue and/or documentation of 2 GAA gene mutations.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

Observational

Participants are observed to track the natural history and outcomes of Pompe disease

Long-term

Follow-up

Participants are monitored for safety and effectiveness after treatment

Long-term

What Are the Treatments Tested in This Trial?

Interventions

  • Observational Registry

Find a Clinic Near You

Who Is Running the Clinical Trial?

Genzyme, a Sanofi Company

Lead Sponsor

Trials
528
Recruited
186,000+
David Meeker profile image

David Meeker

Genzyme, a Sanofi Company

Chief Executive Officer since 2011

MD from the University of Vermont Medical School, Advanced Management Program at Harvard Business School

Jean-Paul Kress profile image

Jean-Paul Kress

Genzyme, a Sanofi Company

Chief Medical Officer since 2015

MD from Faculte Necker-Enfants Malades, Paris

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