Apple Cider Vinegar for Blood Sugar Control

Overseen By Marc Moulin, PhD

Age: 18 - 65

Sex: Any

Trial Phase: Academic

Sponsor: Bragg Live Food Products

Must not be taking: Glucose-impacting drugs

Disqualifiers: Pregnancy, Diabetes, Cardiovascular, Cancer, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 1

Duration: 1 day

24 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial investigates whether Bragg Apple Cider Vinegar (ACV) can help control blood sugar levels after a high-carb meal, compared to water. Participants will consume either ACV or water, followed by a blood draw to check blood sugar and insulin levels. The trial seeks individuals with higher than normal blood sugar levels, but not diabetes, and other signs of metabolic syndrome, such as high blood pressure or belly fat. As an unphased trial, it offers participants the chance to contribute to research that could lead to new methods for managing blood sugar levels.

Do I need to stop taking my current medications for the trial?

The trial requires that you maintain your current lifestyle habits, including medications, as much as possible throughout the study. However, if you are taking medications or supplements that might affect glucose metabolism, you may not be eligible to participate.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research shows that apple cider vinegar (ACV) is generally safe to consume. Studies suggest that daily use of ACV might help manage blood sugar levels in people with type 2 diabetes, but it should not replace medications or lifestyle changes. Thus, ACV could be a helpful addition to a diabetes management plan.

Although ACV is not a cure for diabetes, it may slightly lower blood sugar levels and improve insulin use. These findings indicate that ACV is safe for managing blood sugar. However, ACV should not be the sole method for controlling blood sugar. Always consult a healthcare provider before changing a treatment plan. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about using Bragg Apple Cider Vinegar (ACV) for blood sugar control because it's a natural alternative to traditional medications like metformin or insulin. Unlike these standard treatments, Bragg ACV is derived from fermented apples and may help regulate blood sugar levels with a simple dietary addition. Its potential to be a cost-effective and accessible option makes it particularly appealing, especially for those seeking more natural approaches to managing their health.

What evidence suggests that Bragg Apple Cider Vinegar might be an effective treatment for blood sugar control?

Research has shown that apple cider vinegar (ACV) can help manage blood sugar levels. Daily ACV intake has been linked to better blood sugar control and improved insulin response, especially for people with type 2 diabetes. One study found that those who used ACV had lower A1C levels, indicating better long-term blood sugar management. Another study noted improvements in blood sugar and cholesterol levels. These findings suggest that ACV might help reduce blood sugar spikes after meals. In this trial, participants will receive either Bragg Apple Cider Vinegar or a placebo to further evaluate its effects on blood sugar control. ^{1 4 6 7 8}

Who Is on the Research Team?

David Crowley, MD

Principal Investigator

KGK Science Inc.

Are You a Good Fit for This Trial?

This trial is for healthy adults interested in the effects of Bragg Apple Cider Vinegar (ACV) on blood sugar levels after eating carbs. Participants will consume ACV or a placebo and have their blood glucose monitored. Key requirements include not having any chronic health conditions that affect blood sugar.

Inclusion Criteria

Individuals of child-bearing potential must have a negative screening urine pregnancy test and agree to use a medically approved method of birth control for the duration of the study

Stable body weight defined as a <5% change in body weight in the three months prior to baseline

Agrees to maintain current lifestyle habits as much as possible throughout the study

Exclusion Criteria

Individuals who are pregnant, breast feeding, or planning to become pregnant during the study

Allergy, sensitivity or intolerance, preventing consumption of investigational product, placebo, or standardized meal

Poor venous access as assessed by the QI

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants consume 750 mg of Bragg Apple Cider Vinegar (ACV) liquid or water and undergo blood draws to measure glucose, insulin, and other markers

1 day

1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

1-2 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Bragg Apple Cider Vinegar

Trial Overview The study tests if Bragg ACV can better manage blood sugar levels compared to a placebo after participants eat a lot of carbs. They'll take 750 mg of either ACV or water, then get their blood checked for glucose and insulin changes over two hours.

How Is the Trial Designed?

Group I: Placebo Experimental Treatment 1 Intervention

Water (4 ounces) will be consumed

Group II: Bragg ACV Liquid Experimental Treatment 1 Intervention

Apple Cider Vinegar (1 tablespoon) will be consumed

Who Is Running the Clinical Trial?

Bragg Live Food Products

Lead Sponsor

KGK Science Inc.

Industry Sponsor

Trials

82

Recruited

6,400+

Najla Guthrie

KGK Science Inc.

Chief Executive Officer since 1997

Research career at the Centre for Human Nutrition, University of Western Ontario

Dr. Bibiane Zakaria

KGK Science Inc.

Chief Medical Officer since 2023

MD from an unspecified institution

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC10679383/

The improvement effect of apple cider vinegar as a ... Conclusion. Daily consumption of ACV may have beneficial effects in controlling blood glucose indices and lipid profile in patients with type 2 diabetes.

2. clinicaltrials.gov clinicaltrials.gov/study/NCT07043478

A Clinical Trial to Investigate the Efficacy of Bragg Apple ... The goal of this clinical study is to investigate the efficacy of a Bragg Apple Cider Vinegar (ACV) liquid on postprandial glucose (PPG) excursion compared ...

3. heart.org heart.org/en/news/2024/09/11/what-can-apple-cider-vinegar-really-do-for-your-health

What can apple cider vinegar really do for your health? A small study, published in Frontiers in Clinical Diabetes and Healthcare in 2023, showed A1C dropped from 9.21% to 7.79% in people who consumed ...

4. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov/38028980/

The improvement effect of apple cider vinegar as a ... Daily consumption of ACV may have beneficial effects in controlling blood glucose indices and lipid profile in patients with type 2 diabetes.

5. mdpi.com mdpi.com/2072-6643/17/18/3000

Effect of Apple Cider Vinegar Intake on Body Composition ... In particular, ACV has shown promising effects in improving glycemic control and insulin sensitivity [28,29,30], lipid profiles [28,29,30], and reducing ...

6. webmd.com webmd.com/diet/apple-cider-vinegar-and-your-health

Apple Cider Vinegar: Benefits, Risks, and Uses Keep in mind that vinegar can't replace diabetes medications and a healthy lifestyle, but it should be safe to add to your treatment plan.

7. uchicagomedicine.org uchicagomedicine.org/forefront/health-and-wellness-articles/2018/august/debunking-the-health-benefits-of-apple-cider-vinegar

Debunking the health benefits of apple cider vinegar Bottom line: ACV won't cure diabetes, but it may moderately lower blood glucose levels. It won't take the place of any medications for diabetes, ...

8. nutritiondiets.co.uk nutritiondiets.co.uk/health/apple-cider-vinegar-benefits-risks-what-science-really-says/

Apple Cider Vinegar: Benefits, Risks & What Science ... Research suggests vinegar can improve insulin sensitivity and reduce post-meal blood sugar spikes. A randomised trial found that taking vinegar ...