De-Epithelialization Techniques for Gum Recession
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to find the best way to prepare gum tissue for surgery by comparing different techniques. It specifically examines how well each method removes surface layers, heals the donor site, and improves overall dental outcomes. The methods tested include a surgical blade, a mucotome (a special tool for cutting tissue), a diamond bur (a rotating tool), and an Er:YAG laser (a type of dental laser). People planning to undergo dental surgery involving gum tissue removal and who are in good health might be suitable candidates for this trial. As an unphased trial, it offers participants the chance to contribute to innovative dental research that could enhance surgical outcomes.
Will I have to stop taking my current medications?
The trial does not specify if you need to stop taking your current medications, but it excludes people on anticoagulant or antiplatelet therapy and those on certain drug therapies for systemic conditions. It's best to discuss your specific medications with the trial team.
What prior data suggests that these de-epithelialization techniques are safe for gum recession treatment?
Research has shown that the Er:YAG laser is generally safe for treating gums, with studies finding no major side effects compared to other methods. It also causes less heat damage, a concern with some laser treatments.
For the mucotome, clear safety data is limited. However, its testing alongside other methods suggests it is considered safe enough for further study.
The safety of the diamond bur remains less clear from current studies, but its frequent use in dental procedures suggests it is generally tolerated.
Overall, these treatments are being tested for safety and effectiveness in managing gum recession. If these methods are in clinical trials, they have passed initial safety checks. More detailed results will become available as the trials progress.12345Why are researchers excited about this trial?
Researchers are excited about exploring new de-epithelialization techniques for gum recession. Unlike the standard surgical blade method, which is more traditional, the Er:YAG laser offers precision and potentially less tissue damage, reducing recovery time. The mucotome provides a novel approach with potentially improved accuracy in removing the gum's outer layer. Meanwhile, the diamond bur offers a mechanical method that might be more efficient and less invasive compared to standard options. These techniques are being investigated for their abilities to enhance healing and improve outcomes in gum recession treatments.
What evidence suggests that this trial's de-epithelialization techniques could be effective for gum recession?
This trial will compare different de-epithelialization techniques for gum recession. Research has shown that the Mucotome technique, one of the methods tested in this trial, holds promise for treating gum recession by creating more even tissue and removing unwanted cells, often resulting in significant root coverage. Another method under study, the Diamond Bur, might not be as effective for gum recession, though it has succeeded in other dental procedures. The Er:YAG laser, also included in this trial, is considered safe and effective for cleaning root surfaces and bone, often matching or surpassing traditional methods. Each technique offers advantages, and the best choice may depend on individual needs and preferences.16789
Who Is on the Research Team?
Sandra Stuhr, DMD, MS
Principal Investigator
University of Michigan
Are You a Good Fit for This Trial?
This trial is for individuals with good physical and mental health who need dental surgery involving soft tissue grafts. They must be able to follow study instructions but can't join if they have infections, recent heavy antibiotic use, uncontrolled diabetes, are pregnant or nursing, have severe blood disorders, cancer treatments within the last 18 months, smoke heavily, or have liver/kidney diseases.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo soft tissue augmentation surgery using one of four de-epithelialization techniques: mucotome, Er:YAG laser, surgical diamond bur, or blade
Follow-up
Participants are monitored for wound healing and patient-reported outcomes on post-operative days 1, 7, 14, and 21
What Are the Treatments Tested in This Trial?
Interventions
- Diamond Bur
- Er:YAG Laser
- Mucotome
- Surgical Blade
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Michigan
Lead Sponsor
Delta Dental Foundation
Collaborator