← Back to Search

Bone Property Testing for Fracture Risk

N/A
Waitlist Available
Led By Tamara Rozental, M.D.
Research Sponsored by Beth Israel Deaconess Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Women with hip and wrist fractures within 2 weeks of presentation
Males >50 years with otherwise similar eligibility criteria
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1
Awards & highlights

Study Summary

This trial is testing a new way to measure if someone is at risk for breaking a hip or radius. They think that women who have already fractured these bones have different bone properties than those who haven't, and that this new method can identify these differences.

Who is the study for?
This trial is for women who've recently had hip or wrist fractures and men over 50 with similar conditions. It's not for those on long-term steroids, anticonvulsants, or with certain bone diseases. People treated with specific osteoporosis medications in the past 3 years or healthy controls with prior adult fractures are also excluded.Check my eligibility
What is being tested?
The study tests a new method called Reference Point Indentation to see if it can predict fracture risk better than standard bone density scans. It involves measuring the properties of cortical bone tissue to identify individuals at higher risk of hip and wrist fractures.See study design
What are the potential side effects?
Since Reference Point Indentation is minimally invasive, side effects may include local discomfort, bruising, or swelling at the test site. The procedure is generally considered safe but might not be suitable for people sensitive to minor medical procedures.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I am a woman who has had a hip or wrist fracture in the last 2 weeks.
Select...
I am a man over 50 years old and meet the other study requirements.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Bone mineral density (BMD) by dual-energy x-ray absorptiometry (DXA)
Cortical bone tissue properties by reference point indentation

Trial Design

2Treatment groups
Experimental Treatment
Group I: Post-menopausal womenExperimental Treatment1 Intervention
We will use the handheld Osteoprobe device to measure cortical bone reference point indentation properties.
Group II: Males over 50 yearsExperimental Treatment1 Intervention
We will recruit males to this second study arm, to use the handheld Osteoprobe device to measure cortical bone reference point indentation properties.

Find a Location

Who is running the clinical trial?

Beth Israel Deaconess Medical CenterLead Sponsor
835 Previous Clinical Trials
13,006,340 Total Patients Enrolled
1 Trials studying Osteoporosis
220 Patients Enrolled for Osteoporosis
Brigham and Women's HospitalOTHER
1,598 Previous Clinical Trials
11,462,148 Total Patients Enrolled
7 Trials studying Osteoporosis
63,704 Patients Enrolled for Osteoporosis
Tamara Rozental, M.D.Principal InvestigatorBeth Israel Deaconess Medical Center

Media Library

Reference Point Indentation Clinical Trial Eligibility Overview. Trial Name: NCT03076034 — N/A
Reference Point Indentation 2023 Treatment Timeline for Medical Study. Trial Name: NCT03076034 — N/A
Osteoporosis Clinical Trial 2023: Reference Point Indentation Highlights & Side Effects. Trial Name: NCT03076034 — N/A
Osteoporosis Research Study Groups: Post-menopausal women, Males over 50 years

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is there a possibility for me to join this medical trial?

"This medical trial needs 190 participants aged 50 to 100 with a diagnosis of osteoporosis. To be eligible, patients must have experienced hip and wrist fractures within two weeks prior or not be fracture controls."

Answered by AI

Is there an age limit for participation in this medical trial?

"As per the requirements for this medical trial, participants must be aged 50 or over and not surpass 100 years of age."

Answered by AI

Are there any opportunities for individuals to take part in this research endeavor?

"Per clinicaltrials.gov, the trial – initially posted on January 26th 2015 and last revised May 4th 2020 – is not actively recruiting patients. However, 499 other studies are in search of volunteers at this moment in time."

Answered by AI
~24 spots leftby Aug 2025