Vertical Sleeve Gastrectomy for Non-alcoholic Fatty Liver Disease (NAFLD)

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
University of San Fransisco, San Francisco, CANon-alcoholic Fatty Liver Disease (NAFLD)Vertical Sleeve Gastrectomy - Procedure
Eligibility
40 - 67
All Sexes
What conditions do you have?
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Study Summary

This trial is testing whether a lifestyle modification or a Vertical Sleeve Gastrectomy (VSG) is more effective in reducing non-alcoholic steatohepatitis (NASH) score.

Eligible Conditions
  • Non-alcoholic Fatty Liver Disease (NAFLD)

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: Month 12

Month 12
Histologic improvements in NAFLD Activity Score (NAS)

Trial Safety

Safety Progress

1 of 3

Trial Design

2 Treatment Groups

LSM
1 of 2
VSG + LSM
1 of 2

Active Control

Experimental Treatment

48 Total Participants · 2 Treatment Groups

Primary Treatment: Vertical Sleeve Gastrectomy · No Placebo Group · N/A

VSG + LSMExperimental Group · 2 Interventions: Vertical Sleeve Gastrectomy, Lifestyle Modification Counseling · Intervention Types: Procedure, Behavioral
LSM
Behavioral
ActiveComparator Group · 1 Intervention: Lifestyle Modification Counseling · Intervention Types: Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Vertical Sleeve Gastrectomy
2009
N/A
~140

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: month 12

Who is running the clinical trial?

University of MinnesotaLead Sponsor
1,271 Previous Clinical Trials
1,487,944 Total Patients Enrolled
Sayeed Ikramuddin, M.D., M.H.A.Principal InvestigatorUniversity of Minnesota

Eligibility Criteria

Age 40 - 67 · All Participants · 10 Total Inclusion Criteria

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