Endoscopic Balloon Dilation for Esophageal Strictures
(BITES Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
Esophageal atresia (EA) is one of the most common gastrointestinal congenital anomalies that affects 1 in 2500 to 1 in 4000 live births. It is characterized by abnormal development of the esophagus, which requires surgical intervention to be compatible with life. Surgical repair of EA is associated with risk of developing esophageal strictures or narrowing, which nearly affects 40% of cases. Strictures can be treated using endoscopic balloon dilation, which consists of introducing a catheter with a balloon into the esophagus via endoscopy and positioning it across stricture followed by balloon inflation. The inflated balloon is held in position for a set amount of time with the goal to dilate the narrowed area. At this time there are no pediatric studies comparing difference balloon dilation times and outcomes. Our study's goal is to evaluate balloon dilation inflation time in treating esophageal anastomotic strictures to understand if inflation time is associated with outcome.
Who Is on the Research Team?
Jessica Yasuda, MD
Principal Investigator
Boston Children's Hospital
Are You a Good Fit for This Trial?
Inclusion Criteria
What Are the Treatments Tested in This Trial?
Interventions
- Endoscopic Balloon Dilation
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Patients randomized into Group B will undergo endoscopic balloon dilation for a duration of 180 seconds.
Patients who are randomized into Group A will undergo endoscopic balloon dilation for a total of 30 seconds.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Boston Children's Hospital
Lead Sponsor
Children's Hospital of Philadelphia
Collaborator
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