Genetic Study for Juvenile Myoclonic Epilepsy
(BIOJUME Trial)
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to uncover the genetic cause of Juvenile Myoclonic Epilepsy (JME), potentially leading to better treatments and early detection. Researchers collect blood samples from individuals diagnosed with JME and compare them to those without seizures. This comparison helps identify genetic differences that might cause JME. Candidates may be suitable if they have JME with seizures beginning between ages 10 and 25, especially if frequent morning muscle jerks occur.
As an unphased study, this trial offers a unique opportunity to contribute to groundbreaking research that could transform future JME treatments and early detection methods.
Do I need to stop my current medications to join the trial?
The trial information does not specify if you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Why are researchers excited about this trial?
Researchers are excited about this trial because it aims to uncover the biological factors behind juvenile myoclonic epilepsy (JME) by analyzing blood samples. Unlike traditional treatments that focus on managing symptoms with medications like valproic acid or lamotrigine, this research could pave the way for more targeted therapies by understanding the condition at a deeper biological level. By comparing blood samples from those with JME and those without seizures, scientists hope to identify unique biomarkers, potentially leading to more personalized and effective treatments in the future.
Who Is on the Research Team?
K Pal, MD PhD
Principal Investigator
King's College London
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Data Collection
Participants provide a blood sample and clinical data, including EEG, for genetic analysis
Follow-up
Participants are monitored for safety and effectiveness after data collection
What Are the Treatments Tested in This Trial?
Interventions
- Blood draw
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
People who meet the eligibility requirements and have been diagnosed with juvenile myoclonic epilepsy.
People without a lifetime history of seizures.
Find a Clinic Near You
Who Is Running the Clinical Trial?
King's College London
Lead Sponsor
King's College Hospital NHS Trust
Collaborator
Charles University, Czech Republic
Collaborator
The Hospital for Sick Children
Collaborator
Cardiff University
Collaborator
Odense University Hospital
Collaborator
Hopital Universitaire Robert-Debre
Collaborator
Vestre Viken Hospital Trust
Collaborator
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