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Oral Antibiotics for Infective Endocarditis
Study Summary
This trial is important because it could show that oral antibiotics are just as effective as IV antibiotics for treating endocarditis in people who inject drugs.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My fungal heart infection responds to specific oral medication.I have used intravenous drugs in the last 3 months.You have a heart infection that has not been treated.I have an infection treatable with at least 2 drugs for gram-positive and 1 for gram-negative bacteria.My infection can be treated with at least two different oral antibiotics.I have started IV therapy for at least 10 days and have at least 14 more days of treatment left.I had a heart ultrasound within 2 days before joining the study.My infection did not get better with initial IV antibiotics.I am not currently intoxicated and can make informed decisions.I have trouble absorbing oral antibiotics because of my stomach or intestine problems.You have been diagnosed with infective endocarditis using specific criteria.I improved with my first IV treatment.
- Group 1: Control arm
- Group 2: Partial oral treatment arm
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many subjects are being recruited for this investigation?
"That is correct. According to clinicaltrials.gov, this trial remains open for recruitment as of October 24th 2022 and launched on June 1st 2021. The research project requires 50 participants from two different sites."
Who would be the most suitable candidates for this clinical experimentation?
"The requirements for being admitted to this trial are having endocarditis, bacterial and being in the 18-75 year old age range. This medical study is seeking a total of 50 participants."
Are adolescents eligible for participation in this trial?
"This medical research is open to participants who are aged 18 or over, and not more than 75 years old."
Are researchers still recruiting participants for this clinical experiment?
"The details posted on clinicaltrials.gov reveal that this medical trial is actively seeking prospective patients, having been first published in June 2021 and recently updated in October 2022."
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