Transcranial Magnetic Stimulation for Brain Activity Monitoring

Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Pennsylvania
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

The current study presents a unique opportunity to measure the direct effects of transcranial magnetic stimulation (TMS) by using intracranial electrodes to record neural activity in deep brain regions when TMS single pulses are delivered. If TMS can evoke downstream responses in neural networks of the human brain, it can be a feasible way to study circuit engagement and connectivity.

Are You a Good Fit for This Trial?

Inclusion Criteria

I have had or will have brain electrode surgery at Pennsylvania Hospital.
I am between 21 and 75 years old.
3. Patients considered to be in a stable medical condition, in the opinion of the PI
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Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

TMS Session

Participants undergo a TMS single-pulse session with intracranial electrodes to record neural activity

1 day
1 visit (in-person)

Follow-up

Participants are monitored for safety and effectiveness after the TMS session

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Single Pulse TMS

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: TMSExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Pennsylvania

Lead Sponsor

Trials
2,118
Recruited
45,270,000+