60 Participants NeededMy employer runs this trial

PRONTO-EYE for Diabetic Retinopathy

(PRONTO-EYE Trial)

AS
Overseen ByAngelica Scanzera, OD, MPH
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Illinois at Chicago
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program called PRONTO-EYE, which provides free rides to help people reach their eye doctor appointments. The goal is to determine if transportation improves attendance for patients with diabetic retinopathy (eye damage from diabetes) at their scheduled visits. The trial specifically targets Medicaid patients with this eye condition. Candidates may qualify if they have diabetic retinopathy, Medicaid insurance, and live within 25 miles of the clinic. As an unphased trial, this study offers a unique opportunity to contribute to research that could enhance access to essential eye care.

What prior data suggests that the PRONTO-EYE rideshare intervention is safe for patients with diabetic retinopathy?

Research has shown that the PRONTO-EYE program offers a new way to help people with diabetic retinopathy maintain their eye care visits. This program provides free rides to appointments, focusing solely on transportation without involving any medical treatment. As a result, it poses no health risks or side effects like those associated with medicines or surgeries.

Studies have found that transportation problems often cause people to miss medical visits. By offering free rides, PRONTO-EYE aims to address this issue. The primary goal is to facilitate access to appointments, not to provide a drug or medical procedure. Consequently, there is no evidence of any health risks from this program.12345

Why are researchers excited about this trial?

Unlike traditional treatments for diabetic retinopathy that focus on medical or surgical interventions, PRONTO-EYE introduces a novel approach by addressing transportation barriers. This rideshare program is designed to improve patient adherence to eye care visits, which is crucial for effective management of the condition. Researchers are excited about this trial because it explores how improving access to healthcare services can enhance treatment outcomes, potentially offering a scalable solution to increase patient attendance and compliance.

What evidence suggests that the PRONTO-EYE rideshare program is effective for improving adherence to eye care visits in patients with diabetic retinopathy?

Research shows that transportation issues can hinder patients from attending medical appointments. Studies have found that offering rideshare services helps patients maintain their medical visits. In this trial, all eligible patients are invited to participate in PRONTO-EYE, a rideshare transportation program designed to improve adherence to eye care visits among Medicaid patients with diabetic retinopathy. Early results suggest that transportation programs like PRONTO-EYE may help more patients attend their eye care appointments. This is important because regular eye exams are key to managing diabetic retinopathy and preventing vision loss. While data is still being gathered on PRONTO-EYE's direct impact on diabetic retinopathy outcomes, similar programs have shown promise.12367

Are You a Good Fit for This Trial?

Inclusion Criteria

Established patient
Medicaid insurance
Lives within 25 miles of the clinic
See 2 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention Implementation

Implementation of the PRONTO-EYE rideshare transportation program to improve adherence to eye care visits

6 months
Visits as scheduled for ophthalmology appointments

Follow-up

Participants are monitored for adherence to scheduled ophthalmology visits and secondary implementation outcomes

6 months

What Are the Treatments Tested in This Trial?

Interventions

  • PRONTO-EYE

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: PRONTO-EYE rideshare intervention offeredExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Illinois at Chicago

Lead Sponsor

Trials
653
Recruited
1,574,000+

National Eye Institute (NEI)

Collaborator

Trials
572
Recruited
1,320,000+

Citations

NCT07296952 | Using Implementation Science to Adapt a ...

This is a a type 3 hybrid effectiveness-implementation pilot study to evaluate the PRONTO-EYE intervention, a rideshare transportation program, in patients with ...

Toward equity in vision health: Using human-centered design ...

... rideshare transportation program for patients with diabetic retinopathy (PRONTO-EYE) ... outcomes. This abstract was presented at the 2025 ARVO Annual ...

Experiment-Based Interventions to Diabetic Retinopathy - PMC

This review also summarizes novel therapeutic attempts for diabetic retinopathy along with their advantages and disadvantages.

Clinical trial lessons for managing diabetic retinopathy

Key clinical trials can help us determine how to individualize treatment plans for patients with diabetic retinopathy.

Diabetic Retinopathy Clinical Research Trials

Investigators plan to conduct a type 3 hybrid effectiveness-implementation pilot study using a pre-post intervention design to evaluate the PRONTO-EYE ...

Report From the NEI/FDA Diabetic Retinopathy Clinical Trial ...

Sun presented a case example of an eye with severe NPDR that received ranibizumab and showed a three-step improvement of DR severity after 36 months of ...

Evaluation of Intravitreal Aflibercept for the Treatment ...

The Diabetic Retinopathy Study found that untreated eyes with PDR have a 37% rate of severe vision loss at 72 months, and a patient who does not ...