Aerobic vs Resistance Exercise for Type 1 Diabetes
What You Need to Know Before You Apply
What is the purpose of this trial?
Participants will be asked to wear a continuous glucose monitor for at least three days on three separate occasions. One testing session will be a no-exercise resting control session (90 minutes). One will be a moderate aerobic exercise session (30 minutes of exercise, 60 minutes of recovery), and the third will be a moderate weight-lifting session (\~30 minutes of exercise, 60 minutes of recovery).The investigators will measure changes in blood glucose during exercise by drawing blood during and after exercise. Post-exercise glucose trends will be examined using continuous glucose monitoring.
Will I have to stop taking my current medications?
The trial requires that you do not use medications (other than insulin) that affect glucose metabolism. If you are taking such medications, you may need to stop them to participate.
Is exercise safe for people with type 1 diabetes?
Both aerobic (like running or cycling) and resistance exercises (like weight lifting) are generally safe for people with type 1 diabetes, but they can affect blood sugar levels differently. Aerobic exercise may lower blood sugar, increasing the risk of hypoglycemia (low blood sugar), while resistance exercise can help stabilize it. It's important to monitor blood sugar levels and adjust insulin or food intake as needed when exercising.12345
How does aerobic vs resistance exercise treatment differ for type 1 diabetes?
This treatment is unique because it combines aerobic (like running or cycling) and resistance exercises (like weight lifting) to help manage type 1 diabetes. Unlike other treatments, this approach can prevent blood sugar drops during exercise and improve overall health, including cardiovascular and psychological benefits.12367
What data supports the effectiveness of this treatment for type 1 diabetes?
Are You a Good Fit for This Trial?
This trial is for post-menopausal women with Type 1 Diabetes who can exercise and visit the lab in Edmonton. They should have stable diabetes management, no severe complications like heart disease or neuropathy, not smoke, drink heavily, or be significantly overweight.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Pre-test Measures
Participants undergo pre-test measures including questions related to menopause, PA levels, medication, blood pressure, heart rate, anthropometric characteristics, HbA1c assessment, maximal aerobic capacity test, strength test, and DXA scan.
Testing Sessions
Participants complete three testing sessions: a no-exercise resting control session, a moderate aerobic exercise session, and a moderate resistance exercise session. Blood samples are drawn, and continuous glucose monitoring is conducted.
Follow-up
Participants are monitored for changes in blood glucose and other secondary outcomes using continuous glucose monitoring for up to 24 hours post-exercise.
What Are the Treatments Tested in This Trial?
Interventions
- Aerobic Exercise
- No exercise
- Resistance Exercise
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Alberta
Lead Sponsor
Women and Children's Health Research Institute, Canada
Collaborator