Positive Affect Treatment for Depression and Anxiety
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a new therapy called Positive Affect Treatment (PAT) for Spanish-speaking individuals dealing with depression or anxiety. The goal is to evaluate how effectively this therapy helps those who struggle to feel pleasure and joy in daily life. Participants should experience depression or anxiety that impairs daily functioning and prefer Spanish for therapy sessions. The trial includes about 15 therapy sessions over four months to enhance feelings of reward and enjoyment. As an unphased trial, this study provides a unique opportunity to explore a novel therapy that could significantly improve emotional well-being.
What prior data suggests that Positive Affect Treatment is safe for individuals with depression and anxiety?
Research has shown that Positive Affect Treatment (PAT) is safe for people. In a study with 98 adults, PAT improved mood more effectively than other treatments. Importantly, participants reported no significant harmful effects during the study. Another study found that PAT increased positive emotions and well-being without major side effects.
These findings suggest that PAT is well-tolerated. While more research is always helpful, the current evidence is encouraging for those considering joining a trial.12345Why are researchers excited about this trial?
The Positive Affect Treatment is unique because it focuses on enhancing positive emotions and reward processing rather than just reducing negative symptoms, which is a fresh approach compared to traditional treatments like SSRIs or CBT. This method involves 15 sessions of psychotherapy aimed at boosting reward anticipation, attainment, and learning, potentially offering a more engaging and rewarding experience for patients. Researchers are excited about this treatment because it could lead to improved motivation and enjoyment in everyday activities, providing a complementary option to existing therapies for depression and anxiety.
What evidence suggests that Positive Affect Treatment might be an effective treatment for depression and anxiety?
Research has shown that Positive Affect Treatment (PAT) helps treat depression and anxiety. In a study with 98 adults, PAT led to greater improvements compared to another therapy called NAT. Participants reported experiencing more positive emotions and feelings. Another study found that PAT reduced depression and anxiety symptoms and increased positive feelings even six months later. Overall, evidence suggests PAT enhances well-being by boosting the ability to enjoy positive emotions.45678
Who Is on the Research Team?
Alicia E Meuret, Ph.D.
Principal Investigator
Southern Methodist University
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive 15 sessions of Positive Affect Treatment (PAT) designed to augment reward anticipation, reward attainment, and reward learning
Follow-up
Participants are monitored for safety and effectiveness after treatment, including assessments like SCID-5-RV and PANAS-P
What Are the Treatments Tested in This Trial?
Interventions
- Positive Affect Treatment
How Is the Trial Designed?
1
Treatment groups
Experimental Treatment
15 sessions of psychotherapy designed to augment reward anticipation, reward attainment, and reward learning.
Find a Clinic Near You
Who Is Running the Clinical Trial?
Southern Methodist University
Lead Sponsor
Citations
Positive Affect Treatment for Depression, Anxiety, and Low ...
In this randomized clinical trial of 98 adults, PAT produced greater improvements in clinical status than NAT. Of 7 self-reported reward and ...
Positive Affect Treatment for Depression and Anxiety
Results: PAT resulted in greater improvements in positive affect, p = .009, d = .52, and higher positive affect at 6MFU, p = .002, d = .67, than NAT.
Affect Treatment for Depression, Anxiety, and Low Positive ...
Findings In this randomized clinical trial of 98 adults, PAT produced greater improvements in clinical status than NAT. Of 7 self-reported ...
An evaluation of psychological interventions targeting ...
Positive affect treatment (PAT) was found to be effective, with all three RCTs reporting improvement in symptoms (Bryant et al., Citation2023; Craske et al., ...
Positive affect treatment targets reward sensitivity - PMC - NIH
PAT resulted in higher positive affect, lower negative affect and less severe depression, anxiety, and suicidality at six months follow-up (Craske et al., 2019) ...
NCT05203861 | Affect Treatment for Depression and Anxiety
The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing ...
Upregulating the Positive Affect System in Anxiety and ... - PMC
The PAI protocol resulted in significantly greater increases in positive emotions and psychological well-being compared to a no intervention control group.
Individuals fearing positivity do not perceive positive affect ...
Our findings suggest that individuals fearful of happiness perceived a prospective depression treatment specifically targeting positivity as a poorer fit.
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