20 Participants NeededMy employer runs this trial

Coaching with Ketamine Therapy for Depression

Recruiting at 1 trial location
MN
FK
Overseen ByFranklin King, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Massachusetts General Hospital
Must be taking: Ketamine, Esketamine
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study is being conducted at Massachusetts General Hospital (MGH) to explore whether adding psychedelic coaching can enhance the effects of ketamine or esketamine maintenance treatment in individuals with treatment-resistant depression (TRD). The investigators are currently enrolling participants who are receiving ongoing maintenance intravenous (IV) ketamine or intranasal esketamine (Spravato) treatment at the MGH Ketamine Clinic. Participation in the study will involve adding coaching sessions to your existing ketamine maintenance treatment.

Who Is on the Research Team?

MN

Maren Nyer, PhD

Principal Investigator

Massachusetts General Hospital and Harvard Medical School

FK

Franklin King, MD

Principal Investigator

Massachusetts General Hospital and Harvard Medical School

DM

David Mischoulon, MD/PhD

Principal Investigator

Massachusetts General Hospital and Harvard Medical School

Are You a Good Fit for This Trial?

Inclusion Criteria

I am 18 years old or older.
I am able to understand the study and give my consent to join.
3. Fluent in English (spoken and written).
See 7 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive ongoing maintenance intravenous (IV) ketamine or intranasal esketamine (Spravato) treatment with adjunctive psychedelic coaching sessions

3 months
12 coaching sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

1 month

What Are the Treatments Tested in This Trial?

Interventions

  • Psychedelic Integration Coaching

How Is the Trial Designed?

1

Treatment groups

Experimental Treatment

Group I: Psychedelic CoachingExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Massachusetts General Hospital

Lead Sponsor

Trials
3,066
Recruited
13,430,000+

Fireside Project

Collaborator