Behavioral Activation + Medication for Depression & Anxiety in Aging Adults with Orthopedic Procedures
(CPMH Trial)
Trial Summary
What is the purpose of this trial?
This Hybrid 1 Study will test the effectiveness of a bundled intervention comprised of behavioral activation and medication optimization in reducing symptoms of depression and anxiety in older adults undergoing Orthopedic surgery (compared with usual care), while examining implementation outcomes.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment Behavioral Activation + Medication for Depression & Anxiety in Aging Adults with Orthopedic Procedures?
Research shows that Behavioral Activation (BA) is effective in reducing depressive symptoms among older adults, including those in geriatric psychiatry settings and veterans in primary care. BA is a simple and accessible treatment that helps improve depression by encouraging engagement in positive activities.12345
What data supports the effectiveness of this treatment for depression and anxiety in aging adults with orthopedic procedures?
Research shows that Behavioral Activation (BA) is effective in reducing depressive symptoms in older adults, including those in psychiatric facilities and primary care settings. BA is a simple and accessible treatment that helps improve mood by encouraging engagement in positive activities, making it a promising option for aging adults undergoing orthopedic procedures.12345
How is the treatment for depression and anxiety in aging adults with orthopedic procedures unique?
How is the treatment Behavioral Activation + Medication for Depression & Anxiety in Aging Adults with Orthopedic Procedures different from other treatments?
This treatment is unique because it combines Behavioral Activation (BA), which focuses on increasing engagement in positive activities to improve mood, with medication optimization, specifically targeting aging adults undergoing orthopedic procedures. This dual approach addresses both psychological and physical aspects of recovery, which is not commonly seen in standard treatments for depression and anxiety in this population.12356
Research Team
Ryan Calfee, MD
Principal Investigator
Washington University School of Medicine
Eligibility Criteria
This trial is for adults aged 60 or older who are about to have hip or knee replacement surgery and are experiencing noticeable symptoms of depression or anxiety. They must be able to communicate in English. Those with severe cognitive issues, a history of similar study participation, or acute suicidal thoughts cannot join.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Perioperative Treatment
Behavioral activation and medication optimization begin perioperatively
Postoperative Treatment
Behavioral activation and medication optimization continue for 3 months postoperatively
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- Behavioral activation
- Care as usual
- Medication optimization
Find a Clinic Near You
Who Is Running the Clinical Trial?
Washington University School of Medicine
Lead Sponsor
National Institute of Mental Health (NIMH)
Collaborator