Manometry Systems for Swallowing Difficulty

SA
Overseen BySuzan Abdelhalim, MD
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: University of Wisconsin, Madison
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This study aims to directly compare and contrast swallowing pressure and impedance measurements obtained from two high-resolution manometry (HRM) systems: the Laborie LMT Pharyngeal System and the Medtronic ManoScan ESO HRM System in healthy adult volunteers. The primary objective is to determine how differences in catheter diameter, sensor configuration, and acquisition platforms influence measurement outcomes. Twenty-five healthy adults will participate in a single, approximately 2-hour visit; the study will be open for one year for data collection and two years for data analysis.

Who Is on the Research Team?

TM

Timothy McCulloch, MD

Principal Investigator

University of Wisconsin, Madison

Are You a Good Fit for This Trial?

Inclusion Criteria

Without known swallowing disorders

Exclusion Criteria

Known swallowing disorder
Allergy to topical anesthetic
Allergy to food relevant to study participation (e.g. lactose intolerance)
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Data Collection

Participants undergo a single data collection session involving swallowing tasks using HRM systems

1 day
1 visit (in-person, up to 2 hours)

Follow-up

Participants are monitored for any immediate adverse effects post data collection

1 week

What Are the Treatments Tested in This Trial?

Interventions

  • High-Resolution Manometry

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Group I: Medtronic then LaborieExperimental Treatment2 Interventions
Group II: Laborie then MedtronicExperimental Treatment2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

University of Wisconsin, Madison

Lead Sponsor

Trials
1,249
Recruited
3,255,000+