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Behavioral Intervention

Cognitive Therapy vs Exposure Therapy for OCD (RCT_TOC_16 Trial)

N/A

Recruiting

Led By Frederick Aardema, Ph. D.

Research Sponsored by Centre de Recherche de l'Institut Universitaire en santé Mentale de Montréal

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Primary diagnosis of OCD according to Diagnostical and Statistical Manual, version 5 criteria

Not undergoing a current psychological treatment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change from baseline measure at 6 months

Awards & highlights

RCT_TOC_16 Trial Summary

This trial is testing a new cognitive therapy approach against exposure and response prevention, the current standard of care, for patients with obsessive-compulsive disorder.

Who is the study for?

This trial is for individuals with Obsessive-Compulsive Disorder (OCD) who are fluent in English or French, have not changed their medication for the past 12 weeks, and do not have a history of substance abuse or certain mental disorders. Participants must be willing to potentially switch treatments and keep medications stable during the study.Check my eligibility

What is being tested?

The study compares two OCD treatments: Inference-based cognitive therapy (IBCT), which challenges distorted reasoning without exposure to fears, versus Exposure and Response Prevention (ERP), which involves facing fears directly. The effectiveness, tolerability, and satisfaction rates will be evaluated.See study design

What are the potential side effects?

While specific side effects are not listed for these psychological therapies, participants may experience increased anxiety or distress initially when confronting obsessive thoughts or behaviors during treatment.

RCT_TOC_16 Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I have been diagnosed with OCD based on DSM-5 criteria.

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I am not currently receiving treatment for mental health issues.

RCT_TOC_16 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change from baseline at 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change from baseline at 6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline at 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

assess change in level of overvalued ideation

Obsessive-Compulsive Personality

establishing baseline level of overvalued ideation

Other outcome measures

assess change in impairment in different domain

Anxiety

assess change in symptoms of depression

+9 more

RCT_TOC_16 Trial Design

2Treatment groups

Active Control

Group I: Exposure and response preventionActive Control1 Intervention

ERP is a treatment developed to help people confront their fears based on the rationale that exposure to feared objects, activities, or situations in a safe environment helps reduce fear and decrease avoidance. During the treatment, patients will engage in these exposures to feared stimuli within and between sessions according to hierarchies developed during the initial evaluation sessions, and refrain from engaging in compulsive behaviour until their anxiety subsides (i.e. ritual prevention).

Group II: Inference-based cognitive therapyActive Control1 Intervention

The treatment primarily targets the dysfunctional reasoning and overvalued ideas. IBCT does not include exposure, but aims to bring resolution to the initial obsessional doubt or overvalued idea by showing the participant that the obsession is the result of incorrect reasoning.

0 / 2Eligibility criteria met

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Who is running the clinical trial?

Canadian Institutes of Health Research (CIHR)OTHER_GOV

1,344 Previous Clinical Trials

26,453,267 Total Patients Enrolled

4 Trials studying Obsessive-Compulsive Disorder

816 Patients Enrolled for Obsessive-Compulsive Disorder

Centre de Recherche de l'Institut Universitaire en santé Mentale de MontréalLead Sponsor

12 Previous Clinical Trials

851 Total Patients Enrolled

1 Trials studying Obsessive-Compulsive Disorder

111 Patients Enrolled for Obsessive-Compulsive Disorder

Frederick Aardema, Ph. D.Principal InvestigatorUniversité de Montréal

1 Previous Clinical Trials

111 Total Patients Enrolled

1 Trials studying Obsessive-Compulsive Disorder

111 Patients Enrolled for Obsessive-Compulsive Disorder

Media Library

Exposure and response prevention (Behavioral Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT03677947 — N/A

Obsessive-Compulsive Disorder Research Study Groups: Exposure and response prevention, Inference-based cognitive therapy

Obsessive-Compulsive Disorder Clinical Trial 2023: Exposure and response prevention Highlights & Side Effects. Trial Name: NCT03677947 — N/A

Exposure and response prevention (Behavioral Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03677947 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are involved in the current clinical trial?

"Affirmative. Clinicaltrials.gov information affirms that this clinical trial is currently recruiting participants, beginning with the initial post date of September 1st 2018 and most recently updated on October 19th 2022. The trial necessitates 150 candidates at a single location."

Answered by AI

Are there currently recruitment opportunities for this trial?

"Through clinicaltrials.gov, it is evident that this medical trial has been recruiting participants since the 1st of September 2018 and was last edited on October 19th 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder

Frederick Aardema 2018. "Inference-Based Cognitive Therapy Versus Exposure and Response Prevention for Obsessive-Compulsive Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03677947.

All > Obsessive Compulsive Disorder > Ocd