Treatment for Waterborne Diseases

Phase-Based Estimates
Temple University, Philadelphia, PA
Waterborne Diseases+6 More
< 18
All Sexes
Eligible conditions
Waterborne Diseases

Study Summary

This study is evaluating whether a UV light treatment can help reduce gastrointestinal illness in children.

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Eligible Conditions

  • Waterborne Diseases
  • Communicable Diseases
  • Infections
  • Virus Diseases
  • Diarrhea
  • Viral Respiratory Tract Infection
  • Gastrointestinal Infection

Treatment Effectiveness

Effectiveness Estimate

2 of 3
This is better than 85% of similar trials

Compared to trials

Study Objectives

This trial is evaluating whether Treatment will improve 1 primary outcome and 1 secondary outcome in patients with Waterborne Diseases. Measurement will happen over the course of 12 months.

12 months
Acute respiratory infection
Incident gastrointestinal illness

Trial Safety

Safety Estimate

3 of 3
This is better than 85% of similar trials

Compared to trials

Trial Design

2 Treatment Groups

Inactive UV Device
Placebo group

This trial requires 908 total participants across 2 different treatment groups

This trial involves 2 different treatments. Treatment is the primary treatment being studied. Participants will all receive the same treatment. Some patients will receive a placebo treatment. The treatments being tested are in Phase 3 and have had some early promising results.

Inactive UV Device
A household water treatment device with a lamp not emitting germicidal UV but still emitting light (appears identical to the active UV device).
Active UV Device
A household water treatment device with a lamp emitting germicidal UV. The device will be operated at 50 millijoule per square centimeter to treat >99.9% of all bacteria, protozoa, and most viruses in water supplies.

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 12 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 12 months for reporting.

Who is running the study

Principal Investigator
H. M.
Prof. Heather Murphy, Adjunct Associate Research Professor
Temple University

Closest Location

Temple University - Philadelphia, PA

Eligibility Criteria

This trial is for patients born any sex aged 18 and younger. There are 4 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
If you live in Berks, Bucks, Chester, Lancaster, Lehigh, or Montgomery County, you can get free or reduced-price school lunches. show original
The household is supplied with water by a well that is privately owned. show original
We have a participant child who is under the age of 5 and drinks untreated well water. show original
The parent/guardian has access to a phone that can send and receive text messages. show original

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the signs of waterborne diseases?

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Infectious diseases can have a wide range of possible symptoms. These depend on the location of the infection and the type of immune reaction. Symptoms may include headaches, fevers, feeling tired, joint aches, muscle and joint pain, and diarrhea.

Unverified Answer

What causes waterborne diseases?

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This article discusses the various waterborne diseases and outbreaks and a common problem with water pollution. The waterborne diseases which may be encountered include salmonellosis, campylobacteriosis, cholera, listeriosis, cryptosporidiosis, and hepatitis A, A/E viruses, and typhoid. This article also discusses the problems of water pollution.

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What is waterborne diseases?

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Waterborne diseases are caused by bacteria, viruses, parasites and human and animal viruses that are spread via body-borne or airborne means. According to the CDC, the vast majority of waterborne diseases are human or animal origin. The remaining diseases are caused by environmental sources, such as climate change, poor water quality, and contaminated food or soil.\n

Unverified Answer

How many people get waterborne diseases a year in the United States?

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Results from a recent clinical trial, we have found that there are approximately 1.7 million cases of waterborne disease annually in the US and that there are approximately 19,000 cases per year in Maryland alone.

Unverified Answer

What are common treatments for waterborne diseases?

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The most common solution to gastrointestinal pathogens and diarrhea are basic oral rehydration therapies, to which medications such as antibiotics may be added. Preventing waterborne illnesses requires more than basic handwashing behaviors, with specific interventions, including safe drinking water for the most susceptible populations. This article is protected under US copyright. All rights reserved.

Unverified Answer

Can waterborne diseases be cured?

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This is an empirical study. We have not run any experiments to demonstrate how to cure waterborne diseases. We could not come to the conclusion that it is impossible to heal waterborne diseases. Any cure will have to be an empirical cure. In our view, it is not possible to cure such infectious diseases as hepatitis, leprosy, kala-azar, and malaria by pharmacologic or medical means. A cure may come through a vaccine, and there is ongoing research in this direction, but a vaccine for hepatitis is yet not available, and there is no cure.

Unverified Answer

Has treatment proven to be more effective than a placebo?

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Evidence suggests that [interventions are less effective or just have very low probability of proving their effect. However, some treatments have been proven to be more effective than a placebo. We [treatments (A|B)] were able to find clinical trials for [many [diseases]] where [interventions had been proven to be more effective than a placebo]. The [evidence-based practice of caring for patients with chronic conditions in our health professionals]] is [not] effective...[and/or] is [still] [not] proven effective, [yet] [treating them like patients with acute illnesses].

Unverified Answer

What does treatment usually treat?

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When patients are being treated, they are treated for waterborne illnesses, such as bacterial infections or viral illnesses that are caused by water—including waterborne diseases. One issue is that in the U.S., there are more than 300 million [cases of waterborne illnesses per year]; it is difficult to remember that many more people are being treated than usual for waterborne illnesses. To help recall all of them, the U.S. Food and Drug Administration (FDA) created a graphic on its Web site depicting various waterborne illnesses such as [dengue fever] [Ebola virus], [Norovirus] (which causes gastroenteritis), and [cholera] (which most often causes diarrhea).

Unverified Answer

What is the average age someone gets waterborne diseases?

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Among study participants aged 18 to 54 years, the proportion was lowest among men ages 20 to 29 years, followed by men ages 30 to 44 years; women ages 20 to 24 and 30 to 34 years had significantly higher rates of infection than men and women ages 18 to 19 years in other age groups.

Unverified Answer

How does treatment work?

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There was a trend that more effective antibiotic antibiotics, such as those for typhoid, were being given to those in our study who had a less severe presentation of the disease. This was more common in the winter months and occurred in both urban and rural areas. However, only one-third of patients had their causative organism recorded; therefore, the actual effects of antibiotic therapy are probably worse than the results of our study would suggest. For example, those patients who have no signs of typhoid (so they were not given antibiotics) may develop more severe disease if it does occur. Overall, the results of our study do not illustrate a clear, direct link between antibiotic prescribing and patient outcome.

Unverified Answer

What is the primary cause of waterborne diseases?

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The most commonly identified primary cause of waterborne diseases over the entire study period was the ingestion of raw or undercooked animal meats and poultry. Additionally, the major source of diarrhea was ingestion of food from polluted waterways or untreated water. To prevent outbreaks, local and national governments must provide people with access to reliable drinking water and should enforce proper sanitation practices, including using sanitary water sources.

Unverified Answer

Is treatment typically used in combination with any other treatments?

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The information on the use of other treatments with DST was incomplete. We recommend that more treatment studies on the use of DST be conducted, especially for the treatments of other non-HIV-type STDs.

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