Educational Videos for Colorectal Cancer

(PeLear CCC Trial)

Overseen By José G. Guillem, MD, MPH, MBA

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: University of North Carolina, Chapel Hill

Disqualifiers: Non-Spanish speakers, Not Latino, Under 18

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 3

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial helps Spanish-speaking Latinos learn about colorectal cancer (CRC) through educational videos in Spanish. It aims to improve knowledge of CRC symptoms, risk factors, and treatments, while encouraging participation in cancer clinical trials (CCTs). Participants will watch videos and complete questionnaires to assess their understanding and willingness to join CCTs. This trial suits Spanish-speaking Latinos who are 18 years or older and interested in learning about CRC and CCTs. As an unphased trial, it provides a unique opportunity to gain valuable knowledge and contribute to important research without the constraints of traditional clinical trial phases.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems to focus on educational sessions rather than medical treatments.

What prior data suggests that these educational videos are safe for participants?

This study involves watching educational videos about colorectal cancer, with no medical treatments tested. Therefore, safety concerns remain minimal. The videos aim to increase knowledge about colorectal cancer symptoms, risk factors, treatments, and cancer clinical trials (CCTs).

Research has shown that educational activities, such as watching videos, generally pose no physical risks. The main goal is to improve understanding and willingness to participate in clinical trials. This approach is non-invasive, as it does not involve medical procedures or drugs. Participants will simply watch the videos and answer questions.

In summary, the videos are safe and designed to educate, not treat. There should be no negative effects from participating in this study. ¹

Why are researchers excited about this trial?

Researchers are excited about the educational videos for colorectal cancer because they aim to increase awareness and understanding of the disease, especially for Spanish-speaking communities. Unlike traditional treatments like surgery, chemotherapy, or radiation, these videos focus on prevention and education by explaining symptoms, risk factors, and available screenings in an accessible format. By empowering patients with knowledge in their native language, this approach hopes to encourage earlier screenings and more informed participation in treatment options and clinical trials.

What evidence suggests that these educational videos are effective for increasing colorectal cancer knowledge and willingness to participate in clinical trials?

Research has shown that educational videos in Spanish can greatly increase awareness and understanding of colorectal cancer (CRC) among Spanish-speaking communities. One study demonstrated a significant improvement in CRC knowledge among viewers, providing strong evidence of effectiveness. Another study found that using community trainers alongside these videos further boosted CRC awareness in Hispanic communities. This trial will evaluate the impact of educational videos on CRC knowledge. These videos have proven effective in enhancing CRC knowledge among Spanish-speaking patients, indicating a promising way to address gaps in cancer education. Overall, these findings suggest that culturally tailored educational efforts can effectively increase CRC knowledge and may encourage participation in cancer clinical trials. ^{2 3 4 5 6}

Who Is on the Research Team?

José G. Guillem, MD, MPH, MBA

Principal Investigator

University of North Carolina, Chapel Hill

Are You a Good Fit for This Trial?

The PeLear CCC trial is for Spanish-speaking Latinos over 18 years old, aiming to increase colorectal cancer knowledge and participation in clinical trials. It's specifically for those attending Saint Thomas More Church in Chapel Hill.

Inclusion Criteria

I am older than 18 years old.

Identifying as Latino

I speak Spanish.

Exclusion Criteria

Not identifying as Latino

I am under 18 years old.

I do not speak Spanish.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Educational Intervention

Participants attend an educational session at STM Church, complete a baseline questionnaire, watch three educational videos on CRC, and complete a post-video questionnaire.

1 day

1 visit (in-person)

Follow-up

Participants return to STM Church to complete a follow-up questionnaire assessing CRC knowledge, willingness to participate in CCTs, and perceived barriers.

4-5 weeks

1 visit (in-person)

Qualitative Interviews

Twenty participants participate in one-on-one interviews to identify barriers to CCT participation.

1 day

1 visit (in-person)

What Are the Treatments Tested in This Trial?

Interventions

• Colorectal Cancer Educational Videos in Spanish

Trial Overview This study tests the effectiveness of educational videos on colorectal cancer awareness among Latinos. Participants will complete questionnaires before and after viewing the videos to measure changes in knowledge and willingness to join clinical trials.

How Is the Trial Designed?

Group I: Educational Videos Experimental Treatment 1 Intervention

Enrolled participants will watch three educational videos in Spanish pertaining to: (1) Colorectal Cancer (CRC) symptoms; (2) CRC risk factors and (3) CRC facts, screening, treatment, and Cancer Clinical Trials (CCT).

Who Is Running the Clinical Trial?

University of North Carolina, Chapel Hill

Lead Sponsor

Trials

1,588

Recruited

4,364,000+

North Carolina Translational and Clinical Sciences Institute

Collaborator

Trials

61

Recruited

4,600+

Published Research Related to This Trial

Patients who received an educational video alongside standard pre-chemotherapy education showed improved recall of important side effects and management strategies, such as fever and mouth problems, compared to those who only received standard education.

The video group was more proactive in reporting symptoms like nausea and signs of infection, indicating that the video not only enhanced understanding but also encouraged better communication about treatment-related issues.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Evaluation of the addition of video-based education for patients receiving standard pre-chemotherapy education. Kinnane, N., Thompson, L.[2019]

A study analyzing 44 educational videos on colorectal cancer screening found that while the production quality was high, the content and accountability were lacking, with a median score of only 15 out of 33 possible points.

Most videos focused on colonoscopy as a screening method but failed to adequately address various risk factors, social consequences of not screening, and barriers to screening, indicating a need for more comprehensive educational content.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Current Quality of Videos on Colorectal Cancer Screening for General Public. Yan, Q., Jensen, JE., Jensen, KJ., et al.[2023]

Colorectal cancer (CRC) is a major health issue, being the third most common cancer and the fourth leading cause of cancer-related deaths globally, highlighting the need for increased awareness and preventive measures.

Efforts such as the establishment of international colorectal cancer awareness day and initiatives like the 'Alianza para la Prevención del Cáncer de Colon' in Spain have contributed to a stabilization or decrease in CRC incidence and mortality in western countries.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The right colon challenge. Cid Gómez, LA., Fernández Fernández, N., Hernández Ramírez, V.[2018]

This pilot study involving 28 newly diagnosed breast cancer patients found that personalized video education prior to their first oncology consultation is feasible and may enhance understanding of their specific diagnosis, particularly regarding tumor subtype.

While patients receiving personalized videos showed improvements in perceived understanding and decision-making, the overall differences between personalized video education and standard materials were not statistically significant, indicating the need for further research to optimize educational approaches.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Evaluating the Effect of a Video Education Curriculum for First Time Breast Cancer Patients: a Prospective RCT Feasibility Study. Sulakvelidze, N., Burdick, B., Kaklamani, V., et al.[2020]

A colorectal cancer education video created in the Somali language significantly improved understanding of cancer risks (80% positive change) and benefits of screening (90% positive change) among 31 Somali men, indicating its effectiveness as an educational tool.

The study highlights the importance of culturally tailored health education, as 93% of participants found the video useful, suggesting it could enhance colorectal cancer screening in the Somali community.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A Culturally Adapted Colorectal Cancer Education Video for the Somali Community in Minnesota: A Pilot Investigation. Nakajima, M., Haji, A., Mohamud, S., et al.[2022]

A Facebook Live campaign targeting Spanish-monolingual Latinos effectively disseminated cancer prevention and screening information during the COVID-19 pandemic, reaching over 19,000 people and generating significant engagement.

The project highlighted the importance of culturally responsive communication and community partnerships in improving access to cancer information for underserved populations, with plans to evaluate its impact on cancer screening rates in the future.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Engaging the community served: a U.S. Cancer Center's Facebook live cancer awareness campaign for Spanish-speaking Latinos during COVID-19. Mora, J., Romo, R., Dempsey, S., et al.[2023]

A video intervention significantly increased knowledge about prostate cancer screening and treatment among 52 patients in the experimental group, compared to no change in the control group, indicating its effectiveness as an educational tool.

The video also influenced patients' preferences for prostate-specific antigen (PSA) screening, with 31% of the experimental group changing their preference compared to only 2% in the control group, demonstrating its impact on patient decision-making without causing confusion or fear.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Efficacy of a video for teaching patients about prostate cancer screening and treatment. Ruthman, JL., Ferrans, CE.[2018]

A pilot study involving 35 Hispanic cancer patients showed that a Spanish-language multimedia intervention significantly increased knowledge about clinical trials compared to a control group, indicating its potential effectiveness in educating this population.

The intervention also improved participants' intention to participate in clinical trials, suggesting that multimedia materials could help address barriers to enrollment among Hispanic patients, although further research with a larger sample size is needed to confirm these findings.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Feasibility trial of a Spanish-language multimedia educational intervention. Wells, KJ., McIntyre, J., Gonzalez, LE., et al.[2021]

The video intervention 'Telling the Story ... To Live is God's Will' significantly reduced cancer fatalism and increased knowledge about colorectal cancer among participants aged 52-92, compared to a control group that viewed a different video.

Both the intervention and control groups had over 60% participation in fecal-occult blood testing (FOBT), indicating that the video intervention was effective in promoting screening behaviors while also addressing underlying beliefs about cancer.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

An intervention to decrease cancer fatalism among rural elders. Powe, BD., Weinrich, S.[2022]

Community members and medical professionals contributed valuable feedback in the development of an educational video aimed at increasing colorectal cancer (CRC) screening awareness, addressing barriers identified by patients.

The video was well-received for its cultural appropriateness and clarity, suggesting that educational tools can effectively enhance patient knowledge and communication regarding CRC screening, particularly in diverse and low-income populations.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Development Of An Educational Video To Improve Patient Knowledge And Communication With Their Healthcare Providers About Colorectal Cancer Screening. Katz, ML., Heaner, S., Reiter, P., et al.[2022]

A study analyzing 46 YouTube videos on colorectal cancer (CRC) found that while the videos were generally well-liked, less than half discussed important topics like risk factors and screening tests, indicating a lack of comprehensive patient education resources.

The research highlighted that video length was the only factor linked to higher quality scores, suggesting that longer videos may provide more thorough information, but overall, YouTube may not be a reliable source for CRC education for all patients.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

YouTube Videos as a Source of Information on Colorectal Cancer: What Do Our Patients Learn? Sahin, AN., Sahin, AS., Schwenter, F., et al.[2022]

A multimedia patient education program significantly improved knowledge about colorectal cancer screening among 270 Hispanic/Latino adults aged 50-80, enhancing understanding of anatomy, screening options, and risk information (p<.001).

The program effectively engaged participants regardless of literacy levels, but further research is needed to assess its impact on actual screening behaviors, emphasizing that it should complement, not replace, discussions with healthcare providers.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

A multimedia patient education program on colorectal cancer screening increases knowledge and willingness to consider screening among Hispanic/Latino patients. Makoul, G., Cameron, KA., Baker, DW., et al.[2021]

A breast cancer educational video (BCV) significantly improved knowledge about breast cancer in 62% of patients and reduced distress in 30% of those who watched it, based on a study of 69 patients.

The BCV was well-received by 94-98% of participants in a second group of 87 patients, who felt it helped them think critically and ask questions about their treatment options, indicating its effectiveness in enhancing shared decision-making in clinical practice.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

The Effect of Previsit Education in Breast Cancer Patients: A Study of a Shared-decision-making Tool. Serpico, V., Liepert, AE., Boucher, K., et al.[2016]

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12563970/

The Effectiveness of ¡Salud!, por la Vida, an Educational ... Abstract. Simple Summary. Colorectal cancer is the leading cause of cancer-related death in Puerto Rico, yet screening rates remain low.

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC6167938/

Implementation and Outcomes of a Community-Based ... Utilization of community trainers is an effective alternative to increase CRC education and awareness in Hispanic communities, which may positively impact CRC ...

3. cdc.gov cdc.gov/pcd/issues/2018/17_0218.htm

Interventions Promoting Colorectal Cancer Screening ... We evaluated the literature on colorectal cancer screening interventions among Latino men to characterize intervention components effective in increasing ...

4. sciencedirect.com sciencedirect.com/science/article/abs/pii/S1877782109001027

Impact of an educational video-based strategy on the ... Results: Participants in the video-based intervention group showed significant improvement in knowledge of colorectal cancer scores (P < 0.001) and decreased ...

5. bmcmedinformdecismak.biomedcentral.com bmcmedinformdecismak.biomedcentral.com/articles/10.1186/1472-6947-12-53

Testing a Spanish-language colorectal cancer screening ... One other study found that an educational video about CRC improved patient knowledge about CRC in Spanish speaking patients; however, that ...

6. coloncancercoalition.org coloncancercoalition.org/resources/video-library/

Video Library Spanish Educational Videos · Antecedentes familiares y riesgo de cancer colorrectal · Prevenir el cancer de colon · La Importancia De Las Colonoscopias a Tiemp · El ...