Exercise for Cognitive Impairment in Breast Cancer Survivors

(ICAN Trial)

Overseen By Hava Barkai

Age: 18+

Sex: Female

Trial Phase: Academic

Sponsor: University of California, San Diego

Must not be taking: Tamoxifen, Aromatase inhibitors

Disqualifiers: Unsafe medical condition, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Approved in 1 Jurisdiction This treatment is already approved in other countries

Compensation: Varies

Number of Visits: Unknown

253 Participants Needed

Trial Summary

What is the purpose of this trial?

This study will test whether a physical activity intervention can improve cognition in breast cancer survivors and help the development of physical activity guidelines for cognition in breast cancer survivors.

Eligibility Criteria

This trial is for breast cancer survivors who finished treatment at least 6 months ago but within the last 5 years, have low physical activity levels, own a Fitbit-compatible device with internet, and experience cognitive difficulties post-diagnosis. It's not for those with medical conditions that make unsupervised exercise unsafe or those unable to commit to a year-long study.

Inclusion Criteria

Have a Fitbit compatible device with internet

You have trouble thinking clearly since you were diagnosed with cancer.

You don't do much exercise.

Exclusion Criteria

Medical condition that could make it potentially unsafe to be in an unsupervised physical activity intervention

Unable to commit to a 12-month study

You are currently taking tamoxifen or an aromatase inhibitor, and you plan to stop taking it within the next 6 months.

Treatment Details

Interventions

• Control
• Exercise

Trial Overview The study is examining if an exercise program can boost brain function in breast cancer survivors. Participants will either engage in this physical activity intervention or be part of a control group without the special exercise regimen.

Participant Groups

Group I: Exercise Intervention Experimental Treatment 1 Intervention

This arm will receive a 12-month individually tailored phone and email-based exercise program.

Group II: Health & Wellness Intervention Active Control 1 Intervention

This arm will receive a 12-month health and wellness program.

Who Is Running the Clinical Trial?

University of California, San Diego

Lead Sponsor

Trials

1,215

Recruited

1,593,000+