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Behavioural Intervention

Brain Enhancement Training for Age-Related Cognitive Decline (BETTER Aging Trial)

N/A
Recruiting
Led By Hyun Kyu Lee, PhD
Research Sponsored by Posit Science Corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 5 years and at 3 months
Awards & highlights

BETTER Aging Trial Summary

This trial tests the long-term benefits of a computer-based training program. It is Non-Significant Risk and involves 10 weeks of initial training plus a booster.

Who is the study for?
This trial is for people aged 70 or older who speak English fluently, can see and hear well enough to use a computer, and can control a mouse. They must not have dementia as shown by the MoCA test. Those with severe visual/hearing deficits, recent cognitive training, suicidal thoughts, certain medical conditions or implants that interfere with MRI cannot join.Check my eligibility
What is being tested?
The study tests a web-based brain training program (PACR-CT) on elders to see if it helps their cognition five years after initial training and examines the effects of an additional 10 weeks of booster training. The software poses no significant risk.See study design
What are the potential side effects?
Since this intervention involves non-invasive computerized cognitive exercises designed for elderly individuals, there are minimal expected side effects; however, some participants may experience eye strain or mild frustration.

BETTER Aging Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 5 years and at 3 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and at 5 years and at 3 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in performance on global cognitive composite score
Secondary outcome measures
Blood-based Biomarker for Alzheimer's Disease
Change in Depressive Symptoms
Change in brain function
+7 more
Other outcome measures
Change in Diet
Change in Functional Abilities
Change in Life Satisfaction
+5 more

BETTER Aging Trial Design

1Treatment groups
Experimental Treatment
Group I: Experimental TreatmentExperimental Treatment1 Intervention
Computerized plasticity-based adaptive cognitive training requiring a total maximum of 50 treatment sessions, up to 5 sessions per week, 42 minutes per session.

Find a Location

Who is running the clinical trial?

University of IowaOTHER
447 Previous Clinical Trials
879,542 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
230 Patients Enrolled for Age-related Cognitive Decline
Posit Science CorporationLead Sponsor
38 Previous Clinical Trials
4,028 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
230 Patients Enrolled for Age-related Cognitive Decline
The University of Texas at DallasOTHER
58 Previous Clinical Trials
106,055 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
205 Patients Enrolled for Age-related Cognitive Decline

Media Library

PACR-CT (Behavioural Intervention) Clinical Trial Eligibility Overview. Trial Name: NCT05599490 — N/A
Age-related Cognitive Decline Research Study Groups: Experimental Treatment
Age-related Cognitive Decline Clinical Trial 2023: PACR-CT Highlights & Side Effects. Trial Name: NCT05599490 — N/A
PACR-CT (Behavioural Intervention) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05599490 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there opportunities for participation in this study currently available?

"According to the clinicaltrials.gov portal, this particular study is not presently seeking patients. The trial was first uploaded on January 1st 2023 with its last edit on October 28th 2022. Although it does not currently require participants, there are an abundance of other trials actively recruiting at present - totalling 569 in number."

Answered by AI

Who else is applying?

What site did they apply to?
University of Iowa
What portion of applicants met pre-screening criteria?
Met criteria
~120 spots leftby Apr 2026