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Behavioural Intervention
Brain Enhancement Training for Age-Related Cognitive Decline (BETTER Aging Trial)
N/A
Recruiting
Led By Hyun Kyu Lee, PhD
Research Sponsored by Posit Science Corporation
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up at 5 years and at 3 months
Awards & highlights
BETTER Aging Trial Summary
This trial tests the long-term benefits of a computer-based training program. It is Non-Significant Risk and involves 10 weeks of initial training plus a booster.
Who is the study for?
This trial is for people aged 70 or older who speak English fluently, can see and hear well enough to use a computer, and can control a mouse. They must not have dementia as shown by the MoCA test. Those with severe visual/hearing deficits, recent cognitive training, suicidal thoughts, certain medical conditions or implants that interfere with MRI cannot join.Check my eligibility
What is being tested?
The study tests a web-based brain training program (PACR-CT) on elders to see if it helps their cognition five years after initial training and examines the effects of an additional 10 weeks of booster training. The software poses no significant risk.See study design
What are the potential side effects?
Since this intervention involves non-invasive computerized cognitive exercises designed for elderly individuals, there are minimal expected side effects; however, some participants may experience eye strain or mild frustration.
BETTER Aging Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ at 5 years and at 3 months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~at 5 years and at 3 months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Change in performance on global cognitive composite score
Secondary outcome measures
Blood-based Biomarker for Alzheimer's Disease
Change in Depressive Symptoms
Change in brain function
+7 moreOther outcome measures
Change in Diet
Change in Functional Abilities
Change in Life Satisfaction
+5 moreBETTER Aging Trial Design
1Treatment groups
Experimental Treatment
Group I: Experimental TreatmentExperimental Treatment1 Intervention
Computerized plasticity-based adaptive cognitive training requiring a total maximum of 50 treatment sessions, up to 5 sessions per week, 42 minutes per session.
Find a Location
Who is running the clinical trial?
University of IowaOTHER
447 Previous Clinical Trials
879,542 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
230 Patients Enrolled for Age-related Cognitive Decline
Posit Science CorporationLead Sponsor
38 Previous Clinical Trials
4,028 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
230 Patients Enrolled for Age-related Cognitive Decline
The University of Texas at DallasOTHER
58 Previous Clinical Trials
106,055 Total Patients Enrolled
2 Trials studying Age-related Cognitive Decline
205 Patients Enrolled for Age-related Cognitive Decline
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am 70 years old or older.I cannot stay still for an MRI that lasts 1 hour.I am fluent in English.I have a health condition that could soon worsen my physical or mental abilities.I can see, hear, and use a computer mouse well enough to participate.I need help with dressing or personal hygiene.
Research Study Groups:
This trial has the following groups:- Group 1: Experimental Treatment
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Are there opportunities for participation in this study currently available?
"According to the clinicaltrials.gov portal, this particular study is not presently seeking patients. The trial was first uploaded on January 1st 2023 with its last edit on October 28th 2022. Although it does not currently require participants, there are an abundance of other trials actively recruiting at present - totalling 569 in number."
Answered by AI
Who else is applying?
What site did they apply to?
University of Iowa
What portion of applicants met pre-screening criteria?
Met criteria
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