Surveillance and Prevention for Cancer Risk
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial focuses on individuals who may have a higher risk of developing cancer due to family history or existing conditions. Researchers aim to identify early signs that could predict cancer and prevent it from becoming serious. Participants will provide samples such as blood, saliva, or tissue during regular visits. This trial suits those with a family history of cancer, cancer survivors with past treatments, or anyone showing early-stage cancer signs. As a Phase 2 trial, the research measures the treatment's effectiveness in an initial, smaller group, allowing participants to contribute to significant early-stage findings.
Do I need to stop my current medications to join the trial?
The trial information does not specify whether you need to stop taking your current medications. It seems that participants with prior cancer history or those receiving therapy for precursor diseases are allowed, so you might not need to stop your medications, but it's best to confirm with the study team.
Why are researchers excited about this trial?
Researchers are excited about this trial because it focuses on cancer prevention and early detection in people who are at a high risk due to hereditary factors or other precursors. Unlike many current approaches that center on treating cancer after it has developed, this trial looks to intercept and prevent cancer by collecting various tissue samples, such as blood and saliva, to monitor changes over time. This proactive strategy aims to identify cancer risks before they manifest into full-blown disease, potentially leading to better outcomes and a higher chance of survival. By involving family members, the trial also seeks to understand genetic influences, offering a more comprehensive approach to cancer prevention.
Who Is on the Research Team?
Sapna Syngal, MD
Principal Investigator
Dana-Farber Cancer Institute
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Sample Collection
Participants provide blood, buccal swabs, urine, stool, biopsy, or other tissue samples for research purposes
Follow-up
Participants are monitored for clinical, molecular, and pathological changes to predict cancer development
What Are the Treatments Tested in This Trial?
Interventions
- Samples
How Is the Trial Designed?
4
Treatment groups
Experimental Treatment
Participants will also be asked to complete an intake survey that will include questions about demographics, medical history and family history data. Tissue samples will be collected during a routine visit. Participants will be asked to donate any of the following tissue types: * Blood * Buccal swab (saliva) or mouthwash * Urine * Stool * Biopsy or surgical tissue (i.e., bone marrow) * Bodily fluids * Other tissues
Participants will also be asked to complete an intake survey that will include questions about demographics, medical history and family history data. Tissue samples will be collected during a routine visit. Participants will be asked to donate any of the following tissue types: * Blood * Buccal swab (saliva) or mouthwash * Urine * Stool * Biopsy or surgical tissue (i.e., bone marrow) * Bodily fluids * Other tissues
These family members will be identified by the patients participating in the study. Blood, buccal cells, or saliva or oral rinses will be collected in one of three ways from family members of patients (i) at the time of consent; (ii) via a mailed blood kit or saliva kit; or (iii) at a separate appointment scheduled by the consented participant
Participants will also be asked to complete an intake survey that will include questions about demographics, medical history and family history data. Tissue samples will be collected during a routine visit. Participants will be asked to donate any of the following tissue types: * Blood * Buccal swab (saliva) or mouthwash * Urine * Stool * Biopsy or surgical tissue (i.e., bone marrow) * Bodily fluids * Other tissues
Find a Clinic Near You
Who Is Running the Clinical Trial?
Dana-Farber Cancer Institute
Lead Sponsor
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.