MitoQ for Vascular Disease

Phase-Based Progress Estimates
Auburn University, Auburn, ALVascular Disease+3 MoreMitoQ - DietarySupplement
45 - 75
All Sexes
What conditions do you have?

Study Summary

This trial will assess if a mitochondrial antioxidant (MitoQ) can reduce CVD risk among Black Americans, who are disproportionately affected by CVD. Researchers will measure blood pressure, vascular function, and biomarkers of kidney function before & after 8 weeks of MitoQ/placebo.

Eligible Conditions
  • Vascular Disease
  • High Blood Pressure
  • Cardiovascular Disease
  • Racism

Treatment Effectiveness

Study Objectives

6 Primary · 14 Secondary · Reporting Duration: Baseline (pre-intervention)

Baseline (pre-intervention)
Habitual dietary intake
Mental health - depression
Subjective childhood experiences
Subjective mood states
Sleep Apnea Syndromes
Subjective sleep chronotype
Subjective sleep quality
Subjective sleepiness
Subjective social status
Subjective socioeconomic status
Baseline pre-intervention (14-days)
Objective sleep duration
Objective sleep efficiency
Physical activity
Week 8
Changes in blood biomarkers of nitric oxide bioavailability
Changes in blood pressure reactivity
Changes in circulating reactive oxygen species
Changes in flow-mediated dilation (FMD)
Changes in pulse wave analysis (PWA)
Changes in pulse wave velocity (PWV)

Trial Safety

Trial Design

2 Treatment Groups

1 of 2
1 of 2

Experimental Treatment

Non-Treatment Group

60 Total Participants · 2 Treatment Groups

Primary Treatment: MitoQ · Has Placebo Group · N/A

Experimental Group · 1 Intervention: MitoQ · Intervention Types: DietarySupplement
PlaceboComparator Group · 1 Intervention: MitoQ · Intervention Types: DietarySupplement
First Studied
Drug Approval Stage
How many patients have taken this drug
Completed Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: baseline (pre-intervention)

Who is running the clinical trial?

Auburn UniversityLead Sponsor
56 Previous Clinical Trials
13,788 Total Patients Enrolled
Austin T Robinson, PhDPrincipal InvestigatorKinesiology Building
3 Previous Clinical Trials
190 Total Patients Enrolled

Eligibility Criteria

Age 45 - 75 · All Participants · 5 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You do not have medical conditions such as diabetes, kidney disease, lung disease or heart disease.
You don't have any problems that would stop you from exercising or giving blood, like heart problems, muscle or joint pains, or taking blood thinners. You also don't have any allergies to MitoQ substances.

Frequently Asked Questions

Are adults of the requisite age being enrolled in this experiment?

"The age range for this study is 45 - 75 years old." - Anonymous Online Contributor

Unverified Answer

Is participation in this study open to the public at this time?

"According to, this medical research is presently recruiting patients and has been since December 6th 2022. The trial was last amended on January 31st 2023." - Anonymous Online Contributor

Unverified Answer

How many participants have been approved to take part in the experiment?

"Affirmative, according to the trial is actively recruiting participants as of now. It was first posted on December 6th 2022 and most recently revised on January 31st 2023. The study requires 60 individuals from a single medical site." - Anonymous Online Contributor

Unverified Answer

What are the key aims of this research project?

"This 8-week trial will measure changes in nitric oxide bioavailability as its primary outcome. Secondary outcomes include assessing levels of subjective sleepiness using the Epworth Sleepiness Scale, gauging an individual's chronotype through the Munich Chronotype Questionnaire, and quantifying insomnia severity with the Insomnia Severity Index." - Anonymous Online Contributor

Unverified Answer

What characteristics are sought in participants of this research endeavor?

"This trial is currently accepting up to 60 volunteers aged 45-75 with high blood pressure. In addition, they must display a BMI of less than 40 Kg/m2, be free from metabolic and cardiovascular diseases, have no medical conditions which impede them from exercising or donating plasma, and not suffer any allergies linked to MitoQ substances for eligibility." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.