200 Participants Needed

Cancer Survivor Cardiomyopathy Detection

(CASCADE Trial)

SS
TH
Overseen ByTiffany Hansen
Age: 18+
Sex: Any
Trial Phase: Academic
Sponsor: Mayo Clinic
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

Trial Summary

What is the purpose of this trial?

The purpose of this study is to improve the cardiovascular care of adult cancer survivors. The goal is to obtain the data necessary to plan and develop a nation-wide network of a screening program that can help provide cost-effective and long-term monitoring.

Research Team

JH

Joerg Herrmann, MD

Principal Investigator

Mayo Clinic

Eligibility Criteria

Inclusion Criteria

I was diagnosed with breast cancer, lymphoma, or sarcoma and have completed anthracycline therapy within the past year or more.
I have a history of atrial fibrillation not in remission, even if my latest ECG was normal.

Treatment Details

Interventions

  • Echocardiogram
  • Electrocardiogram
  • NT-pro-BNP
Participant Groups
2Treatment groups
Experimental Treatment
Group I: Prior to anthracycline-based therapyExperimental Treatment3 Interventions
patients presenting before the start of anthracycline-based therapy, then to be followed thereafter for 1 year and thereby contributing to the pool of patients with 1-year post-anthracycline assessment.
Group II: 1 year follow-upExperimental Treatment3 Interventions
patients who were treated in the year before and are now returning for their 1-year follow-up.

Find a Clinic Near You

Who Is Running the Clinical Trial?

Mayo Clinic

Lead Sponsor

Trials
3,427
Recruited
3,221,000+

Miami Heart Research Institute

Collaborator

Trials
2
Recruited
650+